Diclofenac epolamine

Base Information

• Chemical Name: Diclofenac epolamine
• CAS No.: 119623-66-4
• Molecular Formula: C14H11Cl2NO2^.C6H13NO
• Molecular Weight: 410.34
• European Community (EC) Number: 684-865-5
• UNII: X5F8EKL9ZG
• DSSTox Substance ID: DTXSID80152531
• Wikidata: Q27121125
• NCI Thesaurus Code: C77355
• RXCUI: 40968
• ChEMBL ID: CHEMBL1201180
• Mol file: 119623-66-4.mol

Synonyms:DHEP;diclofenac 1-(2-hydroxyethyl)pyrrolidinium salt;diclofenac hydroxyethylpyrrolidine;diclofenac-epolamine;diclofenac-N-(2-hydroxyethyl) pyrrolidine;DIEP;Flector;N-(2-hydroxyethyl)pyrrolidinium (2-((2,6-dichlorophenyl)amino)phenyl)acetate

Chemical Property of Diclofenac epolamine

Chemical Property:

• Vapor Pressure: 1.59E-07mmHg at 25°C
• Boiling Point: 412 °C at 760 mmHg
• Flash Point: 203 °C
• PSA: 60.77000
• LogP: 4.22370
• Storage Temp.: Hygroscopic, Refrigerator, Under inert atmosphere
• Solubility.: Chloroform (Slightly), DMSO (Slightly, Sonicated), Methanol (Slightly)
• Hydrogen Bond Donor Count: 3
• Hydrogen Bond Acceptor Count: 5
• Rotatable Bond Count: 6
• Exact Mass: 410.1163980
• Heavy Atom Count: 27
• Complexity: 363

Purity/Quality:

98% ^*data from raw suppliers

Diclofenac Epolamine ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: C1CCN(C1)CCO.C1=CC=C(C(=C1)CC(=O)O)NC2=C(C=CC=C2Cl)Cl
• Recent ClinicalTrials: Safety and Efficacy of Generic Diclofenac Epolamine Acute Pain Due to Minor Ankle Sprain
• Recent EU Clinical Trials: A Randomized, Double-Blind, Multi-Centre, Placebo-Controlled, Active Comparator Study to Evaluate the Efficacy and Safety of a diclofenac epolamine (DHEP) 2.6% medicated plaster in the treatment of acute pain in mild/moderate ankle sprains
• Uses: Diclofenac Epolamine is a diclofenac salt with greater water solubility and better cutaneous absorption properties than other commonly used forms of the drug. Diclofenac, a non-steroidal anti-inflammatory drugs (NSAIDs), is the mainstay of analgesic and anti-inflammatory treatment in dentistry.