3-ethylthiopropionate

Base Information

• Chemical Name: 3-ethylthiopropionate
• CAS No.: 7244-82-8
• Molecular Formula: C5H10O2S
• Molecular Weight: 134.199
• Hs Code.: 2930909090
• Mol file: 7244-82-8.mol

Synonyms:3-(ethylsulfanyl)propanoic acid;3-Ethylthiopropionate;4-thiahexanoic acid;3-ethylsulfanyl-propionic acid;3-(ethylthio)propionic acid;ethylthiopropionic acid;Propanoic acid,3-(ethylthio);3-Aethylmercapto-propionsaeure;3-(Ethylthio)propanoic acid;S-Aethyl-thiohydracrylsaeure;

Chemical Property of 3-ethylthiopropionate

Chemical Property:

• Vapor Pressure: 0.00539mmHg at 25°C
• Boiling Point: 254.3°C at 760 mmHg
• Flash Point: 107.6°C
• PSA: 62.60000
• Density: 1.121g/cm³
• LogP: 1.21420

Purity/Quality:

98%min ^*data from raw suppliers

3-(ethylthio)propanoicacid ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of 3-ethylthiopropionate

There total 9 articles about 3-ethylthiopropionate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 91.0%

S,S-diethyl dithiocarbonate (623-80-3) + acrylic acid (79-10-7) → 3-(ethylthio)propanoic acid (7244-82-8)

Guidance literature:

With potassium hydroxide; at 25 - 90 ℃; for 0.333333h;

DOI:10.1055/s-1986-31881

Reference yield: 67.9%

acrylic acid (79-10-7) + ethanethiol (75-08-1) → 3-(ethylthio)propanoic acid (7244-82-8)

Guidance literature:

With potassium hydroxide; In water; dimethyl sulfoxide; at 50 ℃; for 4h;

DOI:10.1007/BF00768983

Reference yield: 60.4%

β-Propiolactone (57-57-8) + ethanethiol (75-08-1) → 3-(ethylthio)propanoic acid (7244-82-8)

Guidance literature:

With aluminium trichloride; In dichloromethane; at 0 ℃; for 1.5h;

DOI:10.1021/jo00338a020

upstream raw materials:

acrylonitrile

ethanethiol

chloropropionic acid

ethyl bromide

Downstream raw materials:

3-(ethylsulfonyl)propanoic acid

3-ethylthiopropionic acid ethyl ester

C₆H₅Pd(P(C₆H₅)3)2OCOCH₂CH₂SCH₂CH₃

3-(ethylsulfinyl)propanoic acid

Refernces

• 1、 Cairoli, Paola,Morelli, Carlo F.,Speranza, Giovanna,Manitto, Paolo,Pieraccini, Stefano,Sironi, Maurizio. "Studies on umami taste. Synthesis of new guanosine 5′-phosphate derivatives and their synergistic effect with monosodium glutamate". supporting information; scheme or table. p. 1043 - 1050. Retrieved 2009/05/08.
• 2、 -. "8-Chlorodibenz[b,f][1,4]oxazepine-10(11H)-carboxylic acid, 2-(thio-, sulfinyl- and sulfonyl-containing acyl)hydrazides". . . Retrieved 2008/06/13.