Vintoperol

Base Information

• Chemical Name: Vintoperol
• CAS No.: 106498-99-1
• Molecular Formula: C₁₈H₂₄N₂O
• Molecular Weight: 284.401
• UNII: IS7C3GTW01
• DSSTox Substance ID: DTXSID001030624
• Nikkaji Number: J364.028K
• Wikidata: Q27280878
• NCI Thesaurus Code: C76585
• ChEMBL ID: CHEMBL2105559
• Mol file: 106498-99-1.mol

Synonyms:1 beta-ethyl-indolo(2,3-a)naphthyridin-1 alpha-yl-methanol;1-ethyl-1,2,3,4,6,7,12,12b-octahydroindolo(2,3-a)quinolizine-1-methanol;RGH 2981;RGH-2981;RT 3003;RT-3003;vintoperol

Chemical Property of Vintoperol

Chemical Property:

• Vapor Pressure: 9.13E-09mmHg at 25°C
• Boiling Point: 446.8°C at 760 mmHg
• Flash Point: 224°C
• PSA: 39.26000
• Density: 1.21g/cm³
• LogP: 3.18750
• XLogP3: 2.8
• Hydrogen Bond Donor Count: 2
• Hydrogen Bond Acceptor Count: 2
• Rotatable Bond Count: 2
• Exact Mass: 284.188863393
• Heavy Atom Count: 21
• Complexity: 387

Purity/Quality:

99.90% ^*data from raw suppliers

VINTOPEROL 95.00% ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: CCC1(CCCN2C1C3=C(CC2)C4=CC=CC=C4N3)CO
• Isomeric SMILES: CC[C@@]1(CCCN2[C@@H]1C3=C(CC2)C4=CC=CC=C4N3)CO

Technology Process of Vintoperol

There total 3 articles about Vintoperol which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

(+)-1-acetyloxymethyl-1-ethyl-1,2,3,4,6,7,12,12b-octahydroindolo[2,3-a]quinolizine (58451-77-7,99781-90-5,106498-96-8,106498-97-9) → 14,15-dihydro-1,14-seco-21-nor-eburnamenin-20-ol (58451-76-6,64361-56-4,106498-98-0,106498-99-1,114420-88-1)

Guidance literature:

With sodium hydroxide; In methanol; water;

Reference yield:

1-ethyl-2,3,4,6,7,12-hexahydro-indolo(2,3-a)quinolizinium perchlorate (55390-29-9) → 14,15-dihydro-1,14-seco-21-nor-eburnamenin-20-ol (58451-76-6,64361-56-4,106498-98-0,106498-99-1,114420-88-1)

Guidance literature:

With sodium hydroxide; paraformaldehyde; In methanol; dichloromethane; water;

Reference yield:

→ 14,15-dihydro-1,14-seco-21-nor-eburnamenin-20-ol (58451-76-6,64361-56-4,106498-98-0,106498-99-1,114420-88-1)

Guidance literature:

Entspr. Acetoxyderivat;

upstream raw materials:

(+)-1-acetyloxymethyl-1-ethyl-1,2,3,4,6,7,12,12b-octahydroindolo[2,3-a]quinolizine

1-ethyl-2,3,4,6,7,12-hexahydro-indolo(2,3-a)quinolizinium perchlorate

Downstream raw materials:

1-(3,4,5-Trimethoxybenzoyloxymethyl)-1-ethyl-1,2,3,4,6,7,12,12b-octahydro-indolo[2,3-a]quinolizine

Refernces