2-Naphthol-6-sulfonic acid

Base Information

• Chemical Name: 2-Naphthol-6-sulfonic acid
• CAS No.: 93-01-6
• Molecular Formula: C10H8 O4 S
• Molecular Weight: 224.237
• Hs Code.: 2908999090
• European Community (EC) Number: 202-209-4
• NSC Number: 5871
• UNII: O937I7N48V
• DSSTox Substance ID: DTXSID2047014
• Nikkaji Number: J4.666C
• Wikidata: Q10395576
• ChEMBL ID: CHEMBL3305962
• Mol file: 93-01-6.mol

Synonyms:2-naphthol-6-sulfonic acid;2-naphthol-6-sulfonic acid, ammonium salt;2-naphthol-6-sulfonic acid, disodium salt;2-naphthol-6-sulfonic acid, monosodium salt;2-naphthol-6-sulfonic acid, potassium salt;6-hydroxy-2-naphthalenesulfonic acid

Chemical Property of 2-Naphthol-6-sulfonic acid

Chemical Property:

• Appearance/Colour: White to gray-yellow powder
• Melting Point: >300 ºC(lit.)
• Refractive Index: 1.5400 (estimate)
• PKA: 0.41±0.40(Predicted)
• PSA: 82.98000
• Density: 1.549 g/cm³
• LogP: 2.87290
• XLogP3: 0.3
• Hydrogen Bond Donor Count: 2
• Hydrogen Bond Acceptor Count: 4
• Rotatable Bond Count: 1
• Exact Mass: 224.01432991
• Heavy Atom Count: 15
• Complexity: 319

Purity/Quality:

99.9% ^*data from raw suppliers

6-Hydroxynaphthalene-2-sulfonic acid 95+% ^*data from reagent suppliers

Safty Information:

• Pictogram(s): TSCA listed UN NO.
• Hazard Codes: Xi
• Statements: 36/37/38
• Safety Statements: 26-36

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: C1=CC2=C(C=CC(=C2)S(=O)(=O)O)C=C1O

Technology Process of 2-Naphthol-6-sulfonic acid

There total 40 articles about 2-Naphthol-6-sulfonic acid which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

β-naphthol (135-19-3) → 2-naphthol-6-sulfonic acid (93-01-6)

Guidance literature:

With sulfuric acid;

DOI:10.1021/ja01370a041

Reference yield:

1-acetamino-2-hydroxy-naphthalene-6-sulphonic acid (80073-10-5) + 1-amino-2-ethoxy-naphthalene-6-sulphonic acid (118-28-5) → 2-naphthol-6-sulfonic acid (93-01-6)

Guidance literature:

Reference yield:

→ 2-naphthol-6-sulfonic acid (93-01-6)

Guidance literature:

With mineral acid;

DOI:10.1021/ja01370a041 DOI:10.1002/hlca.193802101152

upstream raw materials:

ethanol

2,2'-Dinaphthyl ether

2-naphthol-6,8-disulfonic acid

naphthalene-2,6-disulfonic acid

Downstream raw materials:

sodium 1-(3,5-bistrifluoromethylphenylazo)-2-hydroxy-6-naphthalenesulfonate

2.6-dihydroxynaphthalene

6-chloronaphthalen-2-ol

5-amino-2-naphthol

Refernces

• 1、 -. "Triphendioxazine dyestuffs". . . Retrieved 2008/06/13.
• 2、 Radyshevskaya, O. N.,Gordeev, L. S.,Darmanyan, A. P.,Tyabin, N. V.. "MATHEMATICAL MODELLING OF THE KINETICS OF THE HETEROGENEOUS SULFONATION OF 2-NAPHTHOL WITH SULFURIC ACID". . p. 1412 - 1416. Retrieved 2007/10/02.