Tris(4-methylphenyl)phosphine Oxide

Base Information

• Chemical Name: Tris(4-methylphenyl)phosphine Oxide
• CAS No.: 797-70-6
• Molecular Formula: C21H21OP
• Molecular Weight: 320.371
• Hs Code.: 2931900090
• DSSTox Substance ID: DTXSID00229835
• Nikkaji Number: J50.227H
• Wikidata: Q83110192
• Mol file: 797-70-6.mol

Synonyms:797-70-6;Tri-p-tolylphosphine Oxide;Tris(4-methylphenyl)phosphine Oxide;1-bis(4-methylphenyl)phosphoryl-4-methylbenzene;Phosphine oxide, tris(p-tolyl)-;Tris(p-tolyl)phosphine oxide;BRN 2810669;C21H21OP;Tri-p-tolylphosphineOxide;tri-p-tolylphos-phine oxide;SCHEMBL262688;DTXSID00229835;MFCD00059321;Phosphine oxide, tris(4-methylphenyl)-;AS-58832;LS-106057;CS-0095842;FT-0765933;T0995;T72951;1-[bis(4-methylphenyl)phosphoroso]-4-methylbenzene

Chemical Property of Tris(4-methylphenyl)phosphine Oxide

Chemical Property:

• Melting Point: 145 °C
• Boiling Point: 490 °C at 760 mmHg
• Flash Point: 250.2 °C
• PSA: 26.88000
• Density: 1.12 g/cm³
• LogP: 4.25120
• Storage Temp.: under inert gas (nitrogen or Argon) at 2-8°C
• Solubility.: almost transparency in Methanol
• XLogP3: 5.1
• Hydrogen Bond Donor Count: 0
• Hydrogen Bond Acceptor Count: 1
• Rotatable Bond Count: 3
• Exact Mass: 320.133002287
• Heavy Atom Count: 23
• Complexity: 346

Purity/Quality:

98%,99%, ^*data from raw suppliers

Tris(4-methylphenyl)phosphine Oxide >98.0%(GC) ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: CC1=CC=C(C=C1)P(=O)(C2=CC=C(C=C2)C)C3=CC=C(C=C3)C

Technology Process of Tris(4-methylphenyl)phosphine Oxide

There total 36 articles about Tris(4-methylphenyl)phosphine Oxide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 100.0%

Tri(p-tolyl)phosphine (1038-95-5,218281-19-7) → tri(4-methylphenyl)phosphine oxide (797-70-6)

Guidance literature:

With gold(III) complex supported on cellulose extracted from Carthamus tinctorius immobilized on nanofibrous phosphosilicate; air; at 20 ℃; for 1h; Irradiation;

DOI:10.1039/C8RA09721F

Reference yield: 98.0%

tri-p-tolylphosphine sulfide (6224-65-3) → tri(4-methylphenyl)phosphine oxide (797-70-6)

Guidance literature:

With 2-methyl-3-p-nitrophenyloxaziridine; In chloroform-d1; at 40 ℃; for 72h; Irradiation;

Reference yield: 80.0%

[Pd(1,3-bis(2,6-diisopropylphenyl)imidazol-2-ylidene)(P(p-tolyl)3)] + mesitylenecarbonitrile oxide (2904-57-6) → tri(4-methylphenyl)phosphine oxide (797-70-6) + [Pd(IPr)(NC2,4,6-trimethylphenyl)(κ2-O-N=C-2,4,6-trimethylphenyl(-N-C(=O)2,4,6-trimethylphenyl))]

Guidance literature:

In toluene; for 12h; Solvent; Kinetics; Mechanism; Glovebox; Inert atmosphere;

DOI:10.1016/j.ica.2017.05.069

upstream raw materials:

Tri(p-tolyl)phosphine

tri-p-tolylphosphine sulfide

4,4,5,5-Tetramethyl-2,2,2-tri-p-tolyl-2λ⁵-[1,3,2]dioxaphospholane

2-methyl-3-p-nitrophenyloxaziridine

Downstream raw materials:

[Rh(CO)(OP(CH₃C₆H₄)3)(P(C₆H₅)3)2]⁽¹⁺⁾*ClO₄^(1-)=[Rh(CO)(OP(CH₃C₆H₄)3)(P(C₆H₅)3)2]ClO₄

[Rh(CO)2(OP(CH₃C₆H₄)3)2]⁽¹⁺⁾*ClO₄^(1-)=[Rh(CO)2(OP(CH₃C₆H₄)3)2]ClO₄

Refernces

• 1、 Cai, Xiaochen,Majumdar, Subhojit,Serafim, Leonardo F.,Temprado, Manuel,Nolan, Steven P.,Cazin, Catherine S.J.,Captain, Burjor,Hoff, Carl D.. "N-heterocyclic carbene complexes of palladium in oxygen atom transfer reactions involving the making and breaking of N-O bonds". . p. 285 - 293. Retrieved 2017.
• 2、 Kishida, Natsuki,Suzuki, Hayate,Toyota, Shinji,Yamashina, Masahiro,Yoshizawa, Michito. "Synthesis of Azaylide-Based Amphiphiles by the Staudinger Reaction". supporting information. p. 17915 - 17919. Retrieved 2021/07/09.
• 3、 Henyecz, Réka,Huszár, Bianka,Keglevich, Gy?rgy,Mucsi, Zoltán. "Microwave assisted P–C coupling reactions without directly added P-ligands". . . Retrieved 2021/12/24.