1-Methyl-2-tetralone

Base Information

• Chemical Name: 1-Methyl-2-tetralone
• CAS No.: 4024-14-0
• Molecular Formula: C11H12O
• Molecular Weight: 160.216
• Hs Code.: 29143900
• European Community (EC) Number: 223-690-7
• NSC Number: 89281
• Nikkaji Number: J79.905J
• Mol file: 4024-14-0.mol

Synonyms:1-Methyl-2-tetralone;4024-14-0;1-methyl-3,4-dihydronaphthalen-2(1H)-one;1-methyl-3,4-dihydro-1H-naphthalen-2-one;1,2,3,4-Tetrahydro-1-methylnaphthalen-2-one;EINECS 223-690-7;NSC89281;2(1H)-naphthalenone, 3,4-dihydro-1-methyl-;SCHEMBL948086;MFCD00001728;NSC 89281;NSC-89281;ZB1757;AKOS015912462;FT-0608053;1-Methyl-2-tetralone, technical grade, 90%;A824999

Chemical Property of 1-Methyl-2-tetralone

Chemical Property:

• Appearance/Colour: clear brown liquid
• Vapor Pressure: 0.0118mmHg at 25°C
• Refractive Index: n20/D 1.553(lit.)
• Boiling Point: 261 °C(lit.)
• Flash Point: >230 °F
• PSA: 17.07000
• Density: 1.02 g/mL at 25 °C(lit.)
• LogP: 2.30540
• Storage Temp.: 0-6°C
• XLogP3: 2.2
• Hydrogen Bond Donor Count: 0
• Hydrogen Bond Acceptor Count: 1
• Rotatable Bond Count: 0
• Exact Mass: 160.088815002
• Heavy Atom Count: 12
• Complexity: 185

Purity/Quality:

98%,99%, ^*data from raw suppliers

1-methyl-2-tetralone ^*data from reagent suppliers

Safty Information:

• Pictogram(s): Xi
• Hazard Codes: Xi
• Statements: 36/37/38
• Safety Statements: 24/25-22

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: CC1C(=O)CCC2=CC=CC=C12

Technology Process of 1-Methyl-2-tetralone

There total 36 articles about 1-Methyl-2-tetralone which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 99.0%

1,2-epoxy-1-methyl-1,2,3,4-tetrahydro-naphthalene (2042-23-1) → 1-methyl-2-tetralone (4024-14-0)

Guidance literature:

With zinc(II) iodide; In benzene; Heating;

DOI:10.1016/S0040-4039(00)01014-5

Reference yield: 95.0%

1-methyl-1,2-tetralindiol (51086-31-8) → 1-methyl-2-tetralone (4024-14-0)

Guidance literature:

With zinc(II) iodide;

DOI:10.1016/S0040-4039(00)01014-5

Reference yield: 92.0%

(E)-1-ethylidene-2,3-dihydro-1H-indene (38950-73-1) → 1-methyl-2-tetralone (4024-14-0)

Guidance literature:

With [hydroxy(tosyloxy)iodo]benzene; In methanol; at 20 ℃; for 0.333333h;

DOI:10.3390/10010217

upstream raw materials:

4-methyl-1,2-dihydronaphthalene

2-methoxy-1-methylnaphthalene

1,2,3,4-tetrahydronaphthalen-2-one

methyl iodide

Downstream raw materials:

1-Benzyl-1-methyl-1,4-dihydronaphthalen-2-one

1-methyl-2-naphthol

C₁₉H₂₁NO

C₁₉H₂₁NO₂

Refernces

• 1、 May et al.. "". . p. 1621. Retrieved 1961.
• 2、 Paladhi, Sushovan,Liu, Yidong,Kumar, B. Senthil,Jung, Min-Jung,Park, Sang Yeon,Yan, Hailong,Song, Choong Eui. "Fluoride Anions in Self-Assembled Chiral Cage for the Enantioselective Protonation of Silyl Enol Ethers". supporting information. p. 3279 - 3282. Retrieved 2017/06/23.
• 3、 Phatake, Ravindra S.,Ramana, Chepuri V.. "Oxone-acetone mediated Wacker-type oxidation of benzo-fused olefins". supporting information. p. 3868 - 3871. Retrieved 2015/06/08.