Technology Process of N,N-bis<3-(4-fluorophenyl)-4-(methoxycarbonyl)-5-methyl-2,3-dihydrofuran-2-yl>hydroxylamine
There total 1 articles about N,N-bis<3-(4-fluorophenyl)-4-(methoxycarbonyl)-5-methyl-2,3-dihydrofuran-2-yl>hydroxylamine which
guide to synthetic route it.
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synthetic route:
- Guidance literature:
-
With
sodium methylate;
In
methanol;
at 0 ℃;
for 2.25h;
DOI:10.1021/jm00163a011
- Guidance literature:
-
Multi-step reaction with 7 steps
1: 7.3 g / methanol / 1.) 40 deg C, 2 h, 2.) 50 deg C, 5 h
2: 1.) lithium aluminum hydride / diethyl ether / 1.) 0 deg C, 1 h, 2.) RT, 2 h
3: manganese dioxide, triethylamine / diethyl ether / 48 h / Ambient temperature
6: 1.) 1 M triethylborane, 2.) sodium borohydride / 1.) THF, 20 deg C, 140 min, 2.) -75 deg C, 12 h
7: H2, triethylamine / 10percent Pd/C / methanol / 0.33 h / Ambient temperature
With
manganese(IV) oxide; sodium tetrahydroborate; lithium aluminium tetrahydride; triethyl borane; hydrogen; triethylamine;
palladium on activated charcoal;
In
methanol; diethyl ether;
DOI:10.1021/jm00163a011
- Guidance literature:
-
Multi-step reaction with 7 steps
1: 7.3 g / methanol / 1.) 40 deg C, 2 h, 2.) 50 deg C, 5 h
2: 1.) lithium aluminum hydride / diethyl ether / 1.) 0 deg C, 1 h, 2.) RT, 2 h
3: manganese dioxide, triethylamine / diethyl ether / 48 h / Ambient temperature
6: 1.) 1 M triethylborane, 2.) sodium borohydride / 1.) THF, 20 deg C, 140 min, 2.) -75 deg C, 12 h
7: H2, triethylamine / 10percent Pd/C / methanol / 0.33 h / Ambient temperature
With
manganese(IV) oxide; sodium tetrahydroborate; lithium aluminium tetrahydride; triethyl borane; hydrogen; triethylamine;
palladium on activated charcoal;
In
methanol; diethyl ether;
DOI:10.1021/jm00163a011