Brazilin

Base Information Edit

Chemical Name:Brazilin
CAS No.:474-07-7
Deprecated CAS:22562-62-5
Molecular Formula:C₁₆H₁₄O₅
Molecular Weight:286.284
Hs Code.:29329990
European Community (EC) Number:207-477-6
UNII:FZ39SW1K10
DSSTox Substance ID:DTXSID80883393
Nikkaji Number:J631.276D
Wikipedia:Brazilin
Wikidata:Q3643873
Metabolomics Workbench ID:53020
ChEMBL ID:CHEMBL598951
Mol file:474-07-7.mol

Synonyms:brasilin;brazilin

Suppliers and Price of Brazilin

Supply Marketing:Edit

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Usbiological
Brazilin
10mg
$ 490.00

DC Chemicals
Brazilin >98%,StandardReferencesGrade
20 mg
$ 280.00

Crysdot
Brazilin 97%
10mg
$ 250.00

Crysdot
Brazilin 97%
25mg
$ 480.00

Cayman Chemical
Brazilin ≥98%
1mg
$ 28.00

Cayman Chemical
Brazilin ≥98%
5mg
$ 123.00

Cayman Chemical
Brazilin ≥98%
10mg
$ 204.00

Cayman Chemical
Brazilin ≥98%
50mg
$ 879.00

Biosynth Carbosynth
Brazilin
250 mg
$ 925.00

Biosynth Carbosynth
Brazilin
25 mg
$ 160.00

Total 65 raw suppliers

Chemical Property of Brazilin Edit

Chemical Property:

Vapor Pressure:3.44E-13mmHg at 25°C
Melting Point:156-157oC
Refractive Index:1.774
Boiling Point:555.8 °C at 760 mmHg
Flash Point:289.9 °C
PSA：90.15000
Density:1.604 g/cm³
LogP:1.61490
XLogP3:1.5
Hydrogen Bond Donor Count:4
Hydrogen Bond Acceptor Count:5
Rotatable Bond Count:0
Exact Mass:286.08412354
Heavy Atom Count:21
Complexity:416

Purity/Quality:

98%,99%, ^*data from raw suppliers

Brazilin ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:
Safety Statements: 24/25

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:C1C2=CC(=C(C=C2C3C1(COC4=C3C=CC(=C4)O)O)O)O
Isomeric SMILES:C1C2=CC(=C(C=C2[C@H]3[C@@]1(COC4=C3C=CC(=C4)O)O)O)O
Description Brazilin is an isoflavonoid originally isolated from C. sappan that has diverse biological activities, including neuroprotective, anti-inflammatory, antibacterial, and antioxidant properties. Brazilin inhibits Aβ (1-42) fibrillogenesis (IC50 = 1.5 μM) more potently than (-)-epigallocatechin gallate , cucurmin , and resveratrol (Item Nos. 10004235 | 70675). It also prevents remodeling of mature Aβ (1-42) fibrils. Brazilin inhibits the production of cytokines, including PGE2 and TNF-α (IC50s = 12.6 and 87.2 μM). It is effective against Gram-positive and Gram-negative bacteria with MICs ranging from 31.3 to 250 μg/ml. In addition, brazilin inhibits osteoclast differentiation mediated by RANKL and is protective against LPS-induced osteoporosis in mice at a dose of 100 mg/kg.
Uses Brazilin is a hair dyeing composition that comprises a natural dye and fatty amine. inhibits platelet aggregation, PLA2, PKC, protein phosphatase, insulin receptor kinase, nitric oxide synthase, antineoplastic Chiefly as a dye. Has also been recommended as indicator in acid-base titrations; acids = yellow, alkalies = carmine-red.

Technology Process of Brazilin

There total 104 articles about Brazilin which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 90.0%