Technology Process of 4-(5-amino-1H-[1,2,4]triazol-3-ylamino)-2-trifluoromethanesulfonylbenzonitrile
There total 6 articles about 4-(5-amino-1H-[1,2,4]triazol-3-ylamino)-2-trifluoromethanesulfonylbenzonitrile which
guide to synthetic route it.
The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:
synthetic route:
- Guidance literature:
-
With
hydrazine;
In
ethanol;
at 60 ℃;
under 760.051 Torr;
Inert atmosphere;
- Guidance literature:
-
Multi-step reaction with 5 steps
1.1: 1-methyl-pyrrolidin-2-one / 1 h / 200 °C / 760.05 Torr / Microwave irradiation; Inert atmosphere
2.1: hydrogenchloride / ethanol / 65 °C / 760.05 Torr / Inert atmosphere
3.1: triethylamine / benzene / 760.05 Torr / Reflux; Inert atmosphere
4.1: methanol / 0.5 h / 760.05 Torr / Inert atmosphere
4.2: 20 °C / 760.05 Torr / Inert atmosphere
5.1: hydrazine / ethanol / 60 °C / 760.05 Torr / Inert atmosphere
With
hydrogenchloride; triethylamine; hydrazine;
In
1-methyl-pyrrolidin-2-one; methanol; ethanol; benzene;
- Guidance literature:
-
Multi-step reaction with 3 steps
1.1: triethylamine / benzene / 760.05 Torr / Reflux; Inert atmosphere
2.1: methanol / 0.5 h / 760.05 Torr / Inert atmosphere
2.2: 20 °C / 760.05 Torr / Inert atmosphere
3.1: hydrazine / ethanol / 60 °C / 760.05 Torr / Inert atmosphere
With
triethylamine; hydrazine;
In
methanol; ethanol; benzene;
