3-Amino-L-tyrosine

Base Information

• Chemical Name: 3-Amino-L-tyrosine
• CAS No.: 300-34-5
• Molecular Formula: C9H12N2O3
• Molecular Weight: 196.206
• Hs Code.: 2922509090
• Mol file: 300-34-5.mol

Synonyms:Tyrosine,3-amino-, L- (8CI);3-Aminotyrosine;L-3-Aminotyrosine;m-Amino-L-tyrosine;

Chemical Property of 3-Amino-L-tyrosine

Chemical Property:

• Appearance/Colour: White Powder
• Vapor Pressure: 4.38E-08mmHg at 25°C
• Melting Point: 279.2-279.8oC
• Refractive Index: 1.67
• Boiling Point: 427.929 °C at 760 mmHg
• PKA: 2.15±0.20(Predicted)
• Flash Point: 212.604 °C
• PSA: 109.57000
• Density: 1.42 g/cm₃
• LogP: 1.21030
• Storage Temp.: 2-8°C
• Solubility.: Aquesous Acid (Slightly)

Purity/Quality:

98%,99%, ^*data from raw suppliers

3-Amino-L-tyrosine ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of 3-Amino-L-tyrosine

There total 4 articles about 3-Amino-L-tyrosine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

3-nitro-L-tyrosine (621-44-3) → 3-amino-L-tyrosine (300-34-5)

Guidance literature:

With hydrogenchloride; tin;

Reference yield:

L-tyrosine (60-18-4,18875-48-4,25619-78-7,30704-25-7) → 3-amino-L-tyrosine (300-34-5)

Guidance literature:

Multi-step reaction with 2 steps

1: nitric acid

2: tin; hydrochloric acid

With hydrogenchloride; tin; nitric acid;

Reference yield:

5-(dimethylamino)naphth-1-ylsulfonyl chloride (605-65-2) + 3-nitro-L-tyrosine (621-44-3) → 3-amino-L-tyrosine (300-34-5)

Guidance literature:

3-nitro-L-tyrosine; With reduced human iodotyrosine deiodinase substituted with 5-deazaflavin analogue; In water; at 20 ℃; for 0.833333h; pH=6; Inert atmosphere; Enzymatic reaction;

5-(dimethylamino)naphth-1-ylsulfonyl chloride; With lithium carbonate; In water; acetonitrile; at 20 ℃; for 1h; pH=10; Reagent/catalyst; Kinetics; Catalytic behavior; Darkness;

DOI:10.1002/anie.201703628

upstream raw materials:

3-nitro-L-tyrosine

L-tyrosine

5-(dimethylamino)naphth-1-ylsulfonyl chloride

Downstream raw materials:

2,2,3,3,4,4,4-Heptafluoro-butyric acid 2-(2,2,3,3,4,4,4-heptafluoro-butyrylamino)-4-[(S)-2-(2,2,3,3,4,4,4-heptafluoro-butyrylamino)-3-(2,2,3,3,4,4,4-heptafluoro-butyryloxy)-3-oxo-propyl]-phenyl ester

C₉H₁₀N₂O₃

3-(3-cyano-4-hydroxyphenyl)-L-alanine

α-D-L-3-aminotyrosine

Refernces

• 1、 Soederling, Ann-Sofi,Ryberg, Henrik,Gabrielsson, Anders,Laerstad, Mona,Toren, Kjell,Niari, Sohbat,Caidahl, Kenneth. "A derivatization assay using gaschromatography/negative chemical ionization tandem mass spectrometry to quantify 3-nitrotyrosine in human plasma". . p. 1187 - 1196. Retrieved 2007/10/03.