10-(4-methylphenyl)-7,8-benzoquinoline

Base Information

• Chemical Name: 10-(4-methylphenyl)-7,8-benzoquinoline
• CAS No.: 1039045-15-2
• Molecular Formula: C₂₀H₁₅N
• Molecular Weight: 269.346
• Mol file: 1039045-15-2.mol

Synonyms:10-(4-methylphenyl)-7,8-benzoquinoline

Chemical Property of 10-(4-methylphenyl)-7,8-benzoquinoline

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of 10-(4-methylphenyl)-7,8-benzoquinoline

There total 21 articles about 10-(4-methylphenyl)-7,8-benzoquinoline which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 99.0%

7,8-benzoquinoline (230-27-3) + para-bromotoluene (106-38-7) → 10-(4-methylphenyl)-7,8-benzoquinoline (1039045-15-2)

Guidance literature:

With iron(III)-acetylacetonate; 1,2-dichloro-2-methylpropane; magnesium; 4,4'-di-tert-butyl-2,2'-bipyridine; In tetrahydrofuran; 1,4-dioxane; 1,2-dichloro-ethane; at 0 ℃; for 24h; Inert atmosphere;

DOI:10.1002/adsc.201100791

Reference yield: 98.0%

7,8-benzoquinoline (230-27-3) + 5,5-dimethyl-2-(4-methylphenyl)-1,3,2-dioxaborinane (380481-66-3) → 10-(4-methylphenyl)-7,8-benzoquinoline (1039045-15-2)

Guidance literature:

With bis[dichloro(pentamethylcyclopentadienyl)iridium(III)]; copper diacetate; silver fluoride; silver(I) triflimide; In 2,2,2-trifluoroethanol; at 25 ℃; for 12h; Reagent/catalyst; Catalytic behavior; Inert atmosphere;

DOI:10.1021/jacs.9b00364

Reference yield: 97.0%

7,8-benzoquinoline (230-27-3) + p-methylbenzoic anhydride (13222-85-0) → 10-(4-methylphenyl)-7,8-benzoquinoline (1039045-15-2)

Guidance literature:

With chloro(1,5-cyclooctadiene)rhodium(I) dimer; sodium carbonate; In o-xylene; at 145 ℃; for 9h; regioselective reaction; Inert atmosphere; Molecular sieve;

DOI:10.1021/ol9000729

upstream raw materials:

7,8-benzoquinoline

4-methyl-benzoyl chloride

p-methylbenzoic anhydride

benzoyl chloride

Refernces

• 1、 Kim, Min,Kwak, Jaesung,Chang, Sukbok. "Rhodium/N-heterocyclic carbene catalyzed direct intermolecular arylation of sp2 and sp3 C-H bonds with chelation assistance". . p. 8935 - 8939. Retrieved 2009.
• 2、 Kim, Jinwoo,Kim, Dongwook,Chang, Sukbok. "Merging two functions in a single Rh catalyst system: Bimodular conjugate for light-induced oxidative coupling". . p. 19052 - 19057. Retrieved 2020.
• 3、 Kim, Jinwoo,Shin, Kwangmin,Jin, Seongho,Kim, Dongwook,Chang, Sukbok. "Oxidatively Induced Reductive Elimination: Exploring the Scope and Catalyst Systems with Ir, Rh, and Ru Complexes". supporting information. p. 4137 - 4146. Retrieved 2019/03/07.