TRIS(1,1,1,3,3,3-HEXAFLUORO-2-PROPYL) PHOSPHITE

Base Information

• Chemical Name: TRIS(1,1,1,3,3,3-HEXAFLUORO-2-PROPYL) PHOSPHITE
• CAS No.: 66470-81-3
• Molecular Formula: C9H3F18O3P
• Molecular Weight: 532.066
• Hs Code.: 2920901900
• Mol file: 66470-81-3.mol

Synonyms:[(CF3)2CHO]3P;Tris[2,2,2-trifluoro-1-(trifluoromethyl)ethyl] phosphite;tris(1,1,1,3,3,3-hexafluoroisopropyl)phosphite;P(OiC3HF6)3;Tris(1,1,1,3,3,3-hexafluoro-2-propyl)phosphite;

Chemical Property of TRIS(1,1,1,3,3,3-HEXAFLUORO-2-PROPYL) PHOSPHITE

Chemical Property:

• Vapor Pressure: 5.01mmHg at 25°C
• Refractive Index: n20/D 1.300(lit.)
• Boiling Point: 130 °C(lit.)
• Flash Point: 44.5°C
• PSA: 41.28000
• Density: 1.69 g/mL at 25 °C(lit.)
• LogP: 6.74270

Purity/Quality:

98%,99%, ^*data from raw suppliers

Tris(1,1,1,3,3,3-hexafluoro-2-propyl) phosphite ^*data from reagent suppliers

Safty Information:

• Pictogram(s): Xi
• Hazard Codes: Xi
• Statements: 36/37/38
• Safety Statements: 26-36

MSDS Files:

SDS file from LookChem

Useful:

• Uses: Tris(1,1,1,3,3,3-hexafluoro-2-propyl) Phosphite acts as a catalyst in combination with rhodium complex in the hydroformylation of olefins.

Technology Process of TRIS(1,1,1,3,3,3-HEXAFLUORO-2-PROPYL) PHOSPHITE

There total 5 articles about TRIS(1,1,1,3,3,3-HEXAFLUORO-2-PROPYL) PHOSPHITE which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 96.0%

1,1,1,3',3',3'-hexafluoro-propanol (920-66-1) → tris(1,1,1,3,3,3-hexafluoroisopropyl)phosphite (66470-81-3)

Guidance literature:

With pyridine; phosphorus trichloride;

Reference yield: 94.0%

bis(1,1,1,3,3,3-hexafluoropropan-2-yl) hydrogen phosphite (120104-57-6) → tris(1,1,1,3,3,3-hexafluoroisopropyl)phosphite (66470-81-3) + C6H15N*C3H3F6O3P + C9H4F18O5P2

Guidance literature:

With triethylamine;

Reference yield: 94.0%

bis(1,1,1,3,3,3-hexafluoropropan-2-yl) hydrogen phosphite (120104-57-6) + triethylamine (121-44-8) → tris(1,1,1,3,3,3-hexafluoroisopropyl)phosphite (66470-81-3) + C6H15N*C3H3F6O3P + C9H4F18O5P2

Guidance literature:

With tris(1,1,1,3,3,3-hexafluoroisopropyl)phosphite;

upstream raw materials:

1,1,1,3',3',3'-hexafluoro-propanol

bis(1,1,1,3,3,3-hexafluoropropan-2-yl) hydrogen phosphite

triethylamine

sodium 1-trifluoromethyl-2,2,2-trifluoroethoxide

Downstream raw materials:

tetrakis(hexafluoroisopropoxy)-α-chlorobenzylphosphorane

Phosphorous acid (2R,3S,5R)-5-(6-benzoylamino-purin-9-yl)-2-[bis-(4-methoxy-phenyl)-phenyl-methoxymethyl]-tetrahydro-furan-3-yl ester bis-(2,2,2-trifluoro-1-trifluoromethyl-ethyl) ester

Phosphorous acid (2R,3S,5R)-5-(4-benzoylamino-2-oxo-2H-pyrimidin-1-yl)-2-[bis-(4-methoxy-phenyl)-phenyl-methoxymethyl]-tetrahydro-furan-3-yl ester bis-(2,2,2-trifluoro-1-trifluoromethyl-ethyl) ester

Refernces

• 1、 Liu, Yu,Tang, Ke-Wen,Wong, Wai-Yeung,Xie, Jun,Xiong, Biquan,Xu, Shipan,Xu, Weifeng. "Silver-Catalyzed Regioselective Phosphorylation of para-Quinone Methides with P(III)-Nucleophiles". . p. 14983 - 15003. Retrieved 2021/11/12.
• 2、 Mironov, V.F.,Konovalova, I.V.. "SYNTHESIS OF TETRAKIS(HEXAFLUOROISOPROPOXY)CHLOROPHOSPHORANE". . p. 1760 - 1763. Retrieved 2007/10/02.