Technology Process of [(2S,3S,4R,5R)-5-(2-amino-6-oxo-3H-purin-9-yl)-3,4-dihydroxy-oxolan-2-yl]methoxy-[[(2R,3R,4S,6S)-3,4-dihydroxy-6-methyl-5-oxo-oxan-2-yl]oxy-hydroxy-phosphoryl]oxy-phosphinic acid
There total 1 articles about [(2S,3S,4R,5R)-5-(2-amino-6-oxo-3H-purin-9-yl)-3,4-dihydroxy-oxolan-2-yl]methoxy-[[(2R,3R,4S,6S)-3,4-dihydroxy-6-methyl-5-oxo-oxan-2-yl]oxy-hydroxy-phosphoryl]oxy-phosphinic acid which
guide to synthetic route it.
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synthetic route:
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991-43-5,3123-67-9,5572-04-3,5750-57-2,6815-91-4,10108-97-1,20236-92-4,20406-59-1,26234-84-4,26378-86-9,41432-88-6,55331-69-6,78391-95-4
guanosine 5'-diphospho-D-mannose
- Guidance literature:
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With
GDP-D-mannose 4,6-dehydratase; tris hydrochloride; magnesium chloride;
In
water;
at 37 ℃;
for 1h;
pH=7.5;
Enzymatic reaction;
DOI:10.1016/S0008-6215(01)00177-X
- Guidance literature:
-
With
GDP-4-keto-6-deoxy-D-mannose 3,5-epimerase-4-reductase; NADPH;
In
phosphate buffer;
at 37 ℃;
for 1h;
pH=6.0;
Enzymatic reaction;
DOI:10.1016/S0008-6215(01)00177-X
- Guidance literature:
-
With
GDP-L-fucose synthase Cys109Ser mutant; water-d2; nicotinamide adenine dinucleotide;
at 28 ℃;
for 2h;
aq. buffer;
Enzymatic reaction;
DOI:10.1021/ja807799k