Tyr-c(D-Asp-Phe-D-Pro-Lys)-NH₂

Base Information

• Chemical Name: Tyr-c(D-Asp-Phe-D-Pro-Lys)-NH₂
• CAS No.: 1346110-58-4
• Molecular Formula: C₃₃H₄₃N₇O₇
• Molecular Weight: 649.747
• Mol file: 1346110-58-4.mol

Synonyms:Tyr-c(D-Asp-Phe-D-Pro-Lys)-NH₂

Chemical Property of Tyr-c(D-Asp-Phe-D-Pro-Lys)-NH₂

Chemical Property:

Purity/Quality:

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MSDS Files:

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Technology Process of Tyr-c(D-Asp-Phe-D-Pro-Lys)-NH₂

There total 1 articles about Tyr-c(D-Asp-Phe-D-Pro-Lys)-NH₂ which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

polyethylene glycol polyamide resin + N-tert-butoxycarbonyl-L-phenylalanine (13734-34-4) + Boc-Lys(Fmoc)-OH (84624-27-1) + (S)-3-[4-(2-Bromo-benzyloxycarbonyloxy)-phenyl]-2-tert-butoxycarbonylamino-propionic acid (47689-67-8) + N-(tert-butoxycarbonyl)-D-proline (37784-17-1,59433-50-0) + Boc-DAsp(β-OFm) (123417-19-6) → Tyr-c(D-Asp-Phe-D-Pro-Lys)-NH2 (1346110-58-4)

Guidance literature:

polyethylene glycol polyamide resin; Boc-Lys(Fmoc)-OH; With O-(benzotriazol-1-yl)-N,N,N',N'-tetramethyluronium tetrafluoroborate; solid phase reaction;

With trifluoroacetic acid; In dichloromethane; solid phase reaction;

N-tert-butoxycarbonyl-L-phenylalanine; (S)-3-[4-(2-Bromo-benzyloxycarbonyloxy)-phenyl]-2-tert-butoxycarbonylamino-propionic acid; N-(tert-butoxycarbonyl)-D-proline; Boc-DAsp(β-OFm); Further stages;

DOI:10.1016/j.bmc.2011.10.040

upstream raw materials:

N-tert-butoxycarbonyl-L-phenylalanine

Boc-Lys(Fmoc)-OH

(S)-3-[4-(2-Bromo-benzyloxycarbonyloxy)-phenyl]-2-tert-butoxycarbonylamino-propionic acid

N-(tert-butoxycarbonyl)-D-proline

Refernces