Levodropropizine

Base Information Edit

Chemical Name:Levodropropizine
CAS No.:99291-25-5
Molecular Formula:C13H20N2O2
Molecular Weight:236.314
Hs Code.:2933599090
European Community (EC) Number:640-087-8
UNII:3O31P6T4G3
DSSTox Substance ID:DTXSID8023210
Nikkaji Number:J276.144K
Wikipedia:Levodropropizine
Wikidata:Q408131
NCI Thesaurus Code:C81593
Metabolomics Workbench ID:153456
ChEMBL ID:CHEMBL1288810
Mol file:99291-25-5.mol

Synonyms:DF 526;DF-526;dipropizine;dipropizine, (S)-isomer;Ditustat;dropropizine;levodropropizine;Levotuss;Tautoss;Zyplo

Suppliers and Price of Levodropropizine

Supply Marketing:Edit

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

TRC
(S)-(-)-Dropropizine
1g
$ 475.00

TCI Chemical
Levodropropizine
100MG
$ 27.00

TCI Chemical
Levodropropizine
1G
$ 95.00

Sigma-Aldrich
Levodropropizine European Pharmacopoeia (EP) Reference Standard
l0420000
$ 190.00

DC Chemicals
Levodropropizine >98%
1 g
$ 300.00

ChemScene
Levodropropizine 99.98%
50mg
$ 72.00

ChemScene
Levodropropizine 99.98%
100mg
$ 96.00

Chem-Impex
Levodropropizine,≥98%(GC) ≥98%(GC)
100MG
$ 103.67

Chem-Impex
Levodropropizine,≥98%(GC) ≥98%(GC)
1G
$ 655.78

AvaChem
Levodropropizine
10g
$ 295.00

Total 116 raw suppliers

Chemical Property of Levodropropizine Edit

Chemical Property:

Appearance/Colour:white solid
Vapor Pressure:1.5E-07mmHg at 25°C
Melting Point:98-100 °C
Refractive Index:1.576
Boiling Point:412.7 °C at 760 mmHg
PKA:14.21±0.20(Predicted)
Flash Point:220.9 °C
PSA：46.94000
Density:1.168 g/cm³
LogP:0.16470
Storage Temp.:Refrigerator
Solubility.:Slightly soluble in water, freely soluble in dilute acetic acid and in methanol, slightly soluble in ethanol (96 per cent).
XLogP3:0.6
Hydrogen Bond Donor Count:2
Hydrogen Bond Acceptor Count:4
Rotatable Bond Count:4
Exact Mass:236.152477885
Heavy Atom Count:17
Complexity:212

Purity/Quality:

99% ^*data from raw suppliers

(S)-(-)-Dropropizine ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:C1CN(CCN1CC(CO)O)C2=CC=CC=C2
Isomeric SMILES:C1CN(CCN1C[C@@H](CO)O)C2=CC=CC=C2
Recent ClinicalTrials:Phase III Study to Evaluate the Efficacy and Safety of HOB-048 CR Tab. in Comparison With HOB-048 Syrup in Patients With Cough Due to Acute or Chronic Bronchitis
Recent EU Clinical Trials:Short-Term Effect of Levodropropizine on Respiratory Centre Output in Normal
Uses S-Form of Dropropizine. Cough suppressive phenylpiperazine derivative. Antitussive Cough Suppressant S-Form of Dropropizine. Cough suppressive phenylpiperazine derivative. Antitussive.

Technology Process of Levodropropizine

There total 8 articles about Levodropropizine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 99.0%