2-Nitro-N-aethyl-N-acetyl-anilin

Base Information

• Chemical Name: 2-Nitro-N-aethyl-N-acetyl-anilin
• CAS No.: 13475-70-2
• Molecular Formula: C₁₀H₁₂N₂O₃
• Molecular Weight: 208.217
• Mol file: 13475-70-2.mol

Synonyms:2-Nitro-N-aethyl-N-acetyl-anilin

Chemical Property of 2-Nitro-N-aethyl-N-acetyl-anilin

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of 2-Nitro-N-aethyl-N-acetyl-anilin

There total 2 articles about 2-Nitro-N-aethyl-N-acetyl-anilin which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

N-ethylacetanilide (529-65-7) → 2-Nitro-N-aethyl-N-acetyl-anilin (13475-70-2) + N-ethyl-N-(4-nitrophenyl)acetamide (1826-56-8)

Guidance literature:

With Iron(III) nitrate nonahydrate; N-hydroxyphthalimide; In 1,2-dichloro-ethane; at 50 ℃; for 10h; Overall yield = 62 %; Overall yield = 38.7 mg; regioselective reaction;

DOI:10.1039/c8ob00841h

Reference yield:

→ 2-Nitro-N-aethyl-N-acetyl-anilin (13475-70-2)

Guidance literature:

2-Nitro-N-aethyl-anilin, Acetanhydrid;

Reference yield: 42.0%

2-Nitro-N-aethyl-N-acetyl-anilin (13475-70-2) → 1-ethyl-2-methyl-1H-benzo[d]imidazole (5805-76-5)

Guidance literature:

With triethyl phosphite; In decane; for 12h; Inert atmosphere; Reflux;

DOI:10.1002/hlca.201100123

upstream raw materials:

N-ethylacetanilide

Downstream raw materials:

1-ethyl-2-methyl-1H-benzo[d]imidazole

Refernces