Chloroacetaldehyde dimethyl acetal

Base Information

• Chemical Name: Chloroacetaldehyde dimethyl acetal
• CAS No.: 97-97-2
• Molecular Formula: C4H9ClO2
• Molecular Weight: 124.567
• Hs Code.: 29110000
• Mol file: 97-97-2.mol

Synonyms:Acetaldehyde,chloro-, dimethyl acetal (6CI,7CI,8CI);1,1-Dimethoxy-2-chloroethane;1-Chloro-2,2-dimethoxyethane;2-Chloro-1,1-dimethoxyethane;2-Chloroacetaldehyde dimethyl acetal;Chloroacetaldehyde dimethyl acetal;NSC60388;

Chemical Property of Chloroacetaldehyde dimethyl acetal

Chemical Property:

• Appearance/Colour: clear colorless to yellowish liquid
• Vapor Pressure: 13.494mmHg at 25°C
• Melting Point: -73 °C
• Refractive Index: n20/D 1.415(lit.)
• Boiling Point: 127.499 °C at 760 mmHg
• Flash Point: 28.889 °C
• PSA: 18.46000
• Density: 1.046 g/cm³
• LogP: 0.84410
• Storage Temp.: Flammables area
• Sensitive.: Moisture Sensitive
• Solubility.: 52g/l
• Water Solubility.: 52 g/L (20 ºC)

Purity/Quality:

99% ^*data from raw suppliers

2-?chloro-?1,?1-?dimethoxy-Ethane ^*data from reagent suppliers

Safty Information:

• Pictogram(s): Xn,F
• Hazard Codes: Xn,F
• Statements: 10-22-52/53-20/21/22-40-36/37/38
• Safety Statements: 28A-26-16-36-23

MSDS Files:

SDS file from LookChem

Useful:

• Uses: Chloroacetaldehyde dimethyl acetal can be used as a reactant to synthesize:2-(chloromethyl)-4,7-dethyl-1,3-dioxepane2-(chloromethyl)-5,6-benzo-1,3-dioxepane ketene dimethyl acetal

Technology Process of Chloroacetaldehyde dimethyl acetal

There total 12 articles about Chloroacetaldehyde dimethyl acetal which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 99.7%

2-chloroethanal (107-20-0) + methanol (67-56-1) → chloroacetaldehyde dimethyl acetal (97-97-2)

Guidance literature:

With toluene-4-sulfonic acid; In chloroform; for 7h; Reflux;

Reference yield: 97.2%

methanol (67-56-1) + chloroethylene (75-01-4,9002-86-2) → chloroacetaldehyde dimethyl acetal (97-97-2)

Guidance literature:

With sodium methylate; chlorine; at 25 - 27 ℃; for 5.5h; pH=3 - 7; Temperature; Large scale;

Reference yield: 92.0%

methanol (67-56-1) + 1,2-dichloro-1-methoxy-ethane (41683-62-9) → chloroacetaldehyde dimethyl acetal (97-97-2)

Guidance literature:

With sodium methylate; at -5 - 20 ℃; for 1h; Green chemistry;

upstream raw materials:

methanol

vinyl acetate

1,2-dichloro-1-methoxy-ethane

methoxyethene

Downstream raw materials:

2-chloromethyl-1,3-dioxolane

1,2-bis(p-tert-butylphenyl)ethylene

2-methylene-1,3-dioxepane

2,2-Dimethoxy-1-(o-nitrophenoxy)ethan

Refernces

• 1、 -. "Green method for preparing chloroacetaldehyde dialkyl alcohol from vinyl acetate". Paragraph 0023-0040. . Retrieved 2020/12/29.
• 2、 -. "Green method for preparing chloroacetaldehyde dialkyl alcohol from vinyl ether". Paragraph 0033-0034; 0036-0038. . Retrieved 2020/12/14.