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(R)-4-Hydroxydihydrofuran-2(3H)-one

Base Information Edit
  • Chemical Name:(R)-4-Hydroxydihydrofuran-2(3H)-one
  • CAS No.:58081-05-3
  • Molecular Formula:C4H6O3
  • Molecular Weight:102.09
  • Hs Code.:29322985
  • UNII:2B1M965970
  • Nikkaji Number:J818.711H
  • Wikidata:Q27254500
  • Mol file:58081-05-3.mol
(R)-4-Hydroxydihydrofuran-2(3H)-one

Synonyms:58081-05-3;(R)-4-Hydroxydihydrofuran-2(3H)-one;(R)-3-Hydroxy-gamma-butyrolactone;(4R)-4-hydroxyoxolan-2-one;(R)-(+)-beta-Hydroxy-gamma-butyrolactone;(R)-3-Hydroxybutyrolactone;2(3H)-Furanone, dihydro-4-hydroxy-, (4R)-;3-Hydroxybutyrolactone, (3R)-;2B1M965970;MFCD00211248;(4R)-4-hydroxytetrahydrofuran-2-one;(3R)-3-hydroxybutyrolactone;SCHEMBL3277293;UNII-2B1M965970;(R)-(+)-3-Hydroxybutyrolacetone;(R)-3-Hydroxy-I(3)-butyrolacton;AKOS015914146;AC-13892;AS-76424;(R)-3-HYDROXY-.GAMMA.-BUTYROLACTONE;CS-0137574;(R)-3-Hydroxy-gamma-butyrolactone, AldrichCPR;E76103;A831725;Q27254500;(R)-(+)-.BETA.-HYDROXY-.GAMMA.-BUTYROLACTONE

Suppliers and Price of (R)-4-Hydroxydihydrofuran-2(3H)-one
Supply Marketing:Edit
Business phase:
The product has achieved commercial mass production*data from LookChem market partment
Manufacturers and distributors:
  • Manufacture/Brand
  • Chemicals and raw materials
  • Packaging
  • price
  • TRC
  • (R)-4-Hydroxydihydrofuran-2(3H)-one
  • 500mg
  • $ 155.00
  • SynQuest Laboratories
  • (R)-3-Hydroxy-gamma-butyrolactone tech%
  • 1 g
  • $ 191.00
  • Crysdot
  • (R)-4-Hydroxydihydrofuran-2(3H)-one 97%
  • 1g
  • $ 171.00
  • Crysdot
  • (R)-4-Hydroxydihydrofuran-2(3H)-one 97%
  • 5g
  • $ 410.00
  • Chemenu
  • (R)-4-Hydroxydihydrofuran-2(3H)-one 97%
  • 10g
  • $ 384.00
  • American Custom Chemicals Corporation
  • (R)-(+)-3-HYDROXY-GAMMA-BUTYROLACTONE 95.00%
  • 5G
  • $ 1090.38
  • Alichem
  • (R)-4-Hydroxydihydrofuran-2(3H)-one
  • 10g
  • $ 345.28
  • Alichem
  • (R)-4-Hydroxydihydrofuran-2(3H)-one
  • 5g
  • $ 228.96
  • Alfa Aesar
  • (R)-(+)-beta-Hydroxy-gamma-butyrolactone, 90+%, ee 97+%
  • 5g
  • $ 220.00
  • Alfa Aesar
  • (R)-(+)-beta-Hydroxy-gamma-butyrolactone, 90+%, ee 97+%
  • 1g
  • $ 66.90
Total 83 raw suppliers
Chemical Property of (R)-4-Hydroxydihydrofuran-2(3H)-one Edit
Chemical Property:
  • Appearance/Colour:Colorless to light yellow liqui 
  • Vapor Pressure:5.42E-05mmHg at 25°C 
  • Refractive Index:1.4655 
  • Boiling Point:310.316 °C at 760 mmHg 
  • PKA:12.87±0.20(Predicted) 
  • Flash Point:157.044 °C 
  • PSA:26.30000 
  • Density:1.394 g/cm3 
  • LogP:0.32180 
  • Storage Temp.:Refrigerator (+4°C) 
  • Solubility.:Miscible with ethanol and chloroform. 
  • XLogP3:-0.8
  • Hydrogen Bond Donor Count:1
  • Hydrogen Bond Acceptor Count:3
  • Rotatable Bond Count:0
  • Exact Mass:102.031694049
  • Heavy Atom Count:7
  • Complexity:88.9
Purity/Quality:

98% *data from raw suppliers

(R)-4-Hydroxydihydrofuran-2(3H)-one *data from reagent suppliers

Safty Information:
  • Pictogram(s): R36/38:Irritating to eyes and skin.; 
  • Hazard Codes:Xi 
  • Statements: 36/38-41 
  • Safety Statements: 26-36-39 
MSDS Files:

SDS file from LookChem

Useful:
  • Canonical SMILES:C1C(COC1=O)O
  • Isomeric SMILES:C1[C@H](COC1=O)O
  • Uses (R)-(+)-β-Hydroxy-γ-butyrolactone is used in the pharmaceutical industry as a chiral building block for the statin class of cholesterol-reducing drugs. It is also used to prepare HIV inhibitors and nutritional supplement such as L-carnitine.
Technology Process of (R)-4-Hydroxydihydrofuran-2(3H)-one

There total 105 articles about (R)-4-Hydroxydihydrofuran-2(3H)-one which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:
Guidance literature:
With hydrogenchloride; sodium hydroxide; In water; ethyl acetate;
Guidance literature:
With hydrogenchloride; sodium hydroxide; In water; ethyl acetate;
Guidance literature:
In water; butanone; at 60 ℃; for 24h;
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