6,10-Dioxaspiro[4.5]decane, 8,8-dimethyl-

Base Information

• Chemical Name: 6,10-Dioxaspiro[4.5]decane, 8,8-dimethyl-
• CAS No.: 702-75-0
• Molecular Formula: C10H18 O2
• Molecular Weight: 170.252
• European Community (EC) Number: 211-869-2
• NSC Number: 7004
• UNII: 2AL9O2R3B1
• DSSTox Substance ID: DTXSID0061034
• Nikkaji Number: J193.068K
• Wikidata: Q81989272
• Mol file: 702-75-0.mol

Synonyms:702-75-0;8,8-dimethyl-6,10-dioxaspiro[4.5]decane;6,10-Dioxaspiro[4.5]decane, 8,8-dimethyl-;8,8-Dimethyl-6,10-dioxaspiro(4.5)decane;2AL9O2R3B1;6,10-Dioxaspiro(4.5)decane, 8,8-dimethyl-;NSC 7004;NSC-7004;EINECS 211-869-2;AI3-22869;5,5-Dimethyl-1,3-dioxane-2-spirocyclopentane;Cyclopentanone, 2,2-dimethyl-1,3-propanediol ketal;NSC7004;6, 8,8-dimethyl-;UNII-2AL9O2R3B1;DTXSID0061034;SCHEMBL21061213;8,8-Dimethyl-6,10-Dioxaspiro[4.5]decan;Cyclopentanone,2-dimethyl-1,3-propanediol ketal;2,2-TETRAMETHYLENE-5,5-DIMETHYL-M-DIOXANE

Chemical Property of 6,10-Dioxaspiro[4.5]decane, 8,8-dimethyl-

Chemical Property:

• Vapor Pressure: 0.508mmHg at 25°C
• Boiling Point: 198.4°C at 760 mmHg
• Flash Point: 70.3°C
• Density: 1g/cm³
• XLogP3: 2.1
• Hydrogen Bond Donor Count: 0
• Hydrogen Bond Acceptor Count: 2
• Rotatable Bond Count: 0
• Exact Mass: 170.130679813
• Heavy Atom Count: 12
• Complexity: 157

Purity/Quality:

98%min ^*data from raw suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: CC1(COC2(CCCC2)OC1)C

Technology Process of 6,10-Dioxaspiro[4.5]decane, 8,8-dimethyl-

There total 3 articles about 6,10-Dioxaspiro[4.5]decane, 8,8-dimethyl- which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 99.08%

2,2-Dimethyl-1,3-propanediol (126-30-7) + cyclopentanone (120-92-3) → cyclopentanone (2,2-dimethylpropylene)acetal (702-75-0)

Guidance literature:

With polyacrylonitrile hybrid fiber mat supported solid acid catalyst; In cyclohexane; Reflux;

DOI:10.1007/s00706-011-0706-0

Reference yield: 89.0%

3,3,9,9-Tetramethyl-1,5,7,11-tetraoxaspiro<5.5>undecan (65849-85-6) + cyclopentanone (120-92-3) → 5,5-dimethyl-1,3-dioxan-2-one (3592-12-9) + cyclopentanone (2,2-dimethylpropylene)acetal (702-75-0)

Guidance literature:

With toluene-4-sulfonic acid; In dichloromethane; at 20 ℃; for 0.666667h; chemoselective reaction;

DOI:10.3184/030823408X382126

Reference yield:

→ cyclopentanone (2,2-dimethylpropylene)acetal (702-75-0)

Guidance literature:

DOI:10.1021/jo01351a024

upstream raw materials:

2,2-Dimethyl-1,3-propanediol

cyclopentanone

3,3,9,9-Tetramethyl-1,5,7,11-tetraoxaspiro<5.5>undecan

Downstream raw materials:

2,2-Dimethyl-1,3-propanediol

cyclopentanone

3,3-dimethyl-1,5-dioxa-spiro[5.5]undecane

Refernces

• 1、 Oliveira, Cristina,Morais, Goreti Ribeiro,Imai, Masao,Inohae, Eiko,Yamamoto, Chishou,Mataka, Shuntaro,Thiemann, Thies. "Acid catalysed reaction of estrones with neopentyl glycol under forced conditions". body text. p. 158 - 162. Retrieved 2010/08/06.
• 2、 Wu, Hai-Hong,Yang, Fan,Cui, Peng,Tang, Jie,He, Ming-Yuan. "An efficient procedure for protection of carbonyls in Br?nsted acidic ionic liquid [Hmim]BF4". . p. 4963 - 4965. Retrieved 2007/10/03.