GTP-GAMMA-S SODIUM SALT

Base Information

• Chemical Name: GTP-GAMMA-S SODIUM SALT
• CAS No.: 37589-80-3
• Molecular Formula: C10H16N5O13P3S
• Molecular Weight: 539.25
• Mol file: 37589-80-3.mol

Synonyms:GTP-g-S;Guanosine5'-(3-thiotriphosphate);Guanosine 5'-(g-thiotriphosphate);5'-O-(hydroxy{[hydroxy(thiophosphonooxy)phosphoryl]oxy}phosphoryl)guanosine;GSP;GTP [S];GTP-γ-S;

Chemical Property of GTP-GAMMA-S SODIUM SALT

Chemical Property:

• Boiling Point: 1014.2 °C at 760 mmHg
• PKA: 0.67±0.50(Predicted)
• Flash Point: 567.1 °C
• PSA: 354.87000
• Density: 2.68 g/cm³
• LogP: 0.76530
• Storage Temp.: −20°C

Purity/Quality:

98%,99%, ^*data from raw suppliers

GTP-GAMMA-S SODIUM SALT 95.00% ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Uses: GTP-γ-S has been used: in G-Protein activation assay to assess the functionality of protease-activated receptor 4 (PAR4)in fluorimetric guanine nucleotide exchange assay of G protein alpha subunits (Gα) to monitor the Rac family small guanosine triphosphatase (GTPase) 2 (Rac2)-stimulated activity of phospholipase Cγ2 mutants

Technology Process of GTP-GAMMA-S SODIUM SALT

There total 1 articles about GTP-GAMMA-S SODIUM SALT which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

→ guanosine-5'-O-(3-thiophosphate) (37589-80-3)

Guidance literature:

DOI:10.1021/ja00752a042

Reference yield:

guanosine-5'-O-(3-thiophosphate) (37589-80-3) + UDP (58-98-0) → guanosine-5'-diphosphate (146-91-8) + uridine-5'-O-(3-thiotriphosphate) (79049-97-1)

Guidance literature:

With 2-amino-2-hydroxymethyl-1,3-propanediol; magnesium chloride; nucleotide 5'-diphosphate kinase; In water; at 30 ℃; for 1h; Enzymatic reaction;

DOI:10.1111/j.1476-5381.1996.tb15175.x

Downstream raw materials:

guanosine-5'-diphosphate

uridine-5'-O-(3-thiotriphosphate)