Lofepramine hydrochloride

Base Information

• Chemical Name: Lofepramine hydrochloride
• CAS No.: 26786-32-3
• Molecular Formula: C26H27 Cl N2 O . Cl H
• Molecular Weight: 455.46
• European Community (EC) Number: 248-002-2
• UNII: Z24K96F991
• DSSTox Substance ID: DTXSID9047833
• Wikidata: Q27114684
• NCI Thesaurus Code: C87616
• ChEMBL ID: CHEMBL2106638
• Mol file: 26786-32-3.mol

Synonyms:Deftan;Feprapax;Gamanil;Gamonil;Hydrochloride, Lofepramine;Leo 640;Lofepramine;Lofepramine Hydrochloride;Lomont;Lopramine

Chemical Property of Lofepramine hydrochloride

Chemical Property:

• Appearance/Colour: off-white solid
• Vapor Pressure: 3.17E-13mmHg at 25°C
• Melting Point: 152-154°
• Boiling Point: 575 °C at 760 mmHg
• Flash Point: 301.6 °C
• PSA: 23.55000
• Density: g/cm³
• LogP: 6.64850
• Storage Temp.: 2-8°C
• Solubility.: DMSO: ~24 mg/mL
• Hydrogen Bond Donor Count: 1
• Hydrogen Bond Acceptor Count: 3
• Rotatable Bond Count: 7
• Exact Mass: 454.1578689
• Heavy Atom Count: 31
• Complexity: 523

Purity/Quality:

98%Min ^*data from raw suppliers

Lofepramine hydrochloride ^*data from reagent suppliers

Safty Information:

• Pictogram(s): Xn
• Hazard Codes: Xn
• Statements: 22-37-53
• Safety Statements: 22-24/25-26-28-36/37/39-38

MSDS Files:

SDS file from LookChem

Total 1 MSDS from other Authors

Useful:

• Canonical SMILES: CN(CCCN1C2=CC=CC=C2CCC3=CC=CC=C31)CC(=O)C4=CC=C(C=C4)Cl.Cl
• Uses: Lofepramine Hydrochloride is a tricyclic anti-depressent drug. Potent inhibitor of noradenaline uptake.
• Therapeutic Function: Antidepressant