Technology Process of 3-{4-[(3,4-dichlorobenzyl)oxy]phenyl}-3-ethoxy propanoic acid
There total 5 articles about 3-{4-[(3,4-dichlorobenzyl)oxy]phenyl}-3-ethoxy propanoic acid which
guide to synthetic route it.
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synthetic route:
- Guidance literature:
-
ethyl 3-{4-[(3,4-dichlorobenzyl)oxy]phenyl}3-ethoxypropionate;
With
water; sodium hydroxide;
In
tetrahydrofuran; ethanol;
at 20 ℃;
for 4h;
With
hydrogenchloride;
In
water;
- Guidance literature:
-
Multi-step reaction with 5 steps
1: tetrahydrofuran / 1.5 h / -78 °C / Inert atmosphere
2: silver(l) oxide / toluene / 20 - 100 °C / Inert atmosphere
3: tetrabutyl ammonium fluoride / tetrahydrofuran / 0 - 20 °C
4: potassium carbonate / acetone / 20 - 60 °C / Inert atmosphere
5: sodium hydroxide; water / ethanol; tetrahydrofuran / 4 h / 20 °C
With
tetrabutyl ammonium fluoride; water; potassium carbonate; sodium hydroxide; silver(l) oxide;
In
tetrahydrofuran; ethanol; acetone; toluene;
- Guidance literature:
-
Multi-step reaction with 3 steps
1: tetrabutyl ammonium fluoride / tetrahydrofuran / 0 - 20 °C
2: potassium carbonate / acetone / 20 - 60 °C / Inert atmosphere
3: sodium hydroxide; water / ethanol; tetrahydrofuran / 4 h / 20 °C
With
tetrabutyl ammonium fluoride; water; potassium carbonate; sodium hydroxide;
In
tetrahydrofuran; ethanol; acetone;
![ethyl 3-{4-[(3,4-dichlorobenzyl)oxy]phenyl}3-ethoxypropionate](/Databaselist/images/loading.webp)
