Methacrylic acid, 2-(dimethylamino)-1-((dimethylamino)methyl)ethyl ester

Base Information

• Chemical Name: Methacrylic acid, 2-(dimethylamino)-1-((dimethylamino)methyl)ethyl ester
• CAS No.: 21476-57-3
• Molecular Formula: C11H22 N2 O2
• Molecular Weight: 214.308
• Hs Code.: 2922199090
• European Community (EC) Number: 244-403-1
• DSSTox Substance ID: DTXSID70175759
• Nikkaji Number: J78.372B
• Wikidata: Q83046072
• Mol file: 21476-57-3.mol

Synonyms:21476-57-3;EINECS 244-403-1;METHACRYLIC ACID, 2-(DIMETHYLAMINO)-1-((DIMETHYLAMINO)METHYL)ETHYL ESTER;Methacrylic acid bis(dimethylaminomethyl)methyl ester;Bis(dimethylamino)isopropylmethacrylate;BRN 2044828;Bis(dimethylaminomethyl)methyl methacrylate;2-(Dimethylamino)-1-((dimethylamino)methyl)ethyl methacrylate;Bis-(dimethylaminomethyl)methylester kyseliny methakrylove [Czech];2-Propenoic acid, 2-methyl-, 2-(dimethylamino)-1-((dimethylamino)methyl)ethyl ester;2-(DIMETHYLAMINO)-1-[(DIMETHYLAMINO)METHYL]ETHYL METHACRYLATE;SCHEMBL770933;DTXSID70175759;LS-89920;1,3-bis(dimethylamino)-2-propyl methacrylate;Bis-(dimethylaminomethyl)methylester kyseliny methakrylove;Methacrylic acid 2-(dimethylamino)-1-[(dimethylamino)methyl]ethyl ester

Chemical Property of Methacrylic acid, 2-(dimethylamino)-1-((dimethylamino)methyl)ethyl ester

Chemical Property:

• Vapor Pressure: 0.0056mmHg at 25°C
• Refractive Index: 1.4620 (estimate)
• Boiling Point: 273.8°C at 760 mmHg
• PKA: 8.59±0.28(Predicted)
• Flash Point: 119.4°C
• PSA: 32.78000
• Density: 0.959g/cm³
• LogP: 0.59750
• XLogP3: 1.6
• Hydrogen Bond Donor Count: 0
• Hydrogen Bond Acceptor Count: 4
• Rotatable Bond Count: 7
• Exact Mass: 214.168127949
• Heavy Atom Count: 15
• Complexity: 215

Purity/Quality:

99% ^*data from raw suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: CC(=C)C(=O)OC(CN(C)C)CN(C)C

Technology Process of Methacrylic acid, 2-(dimethylamino)-1-((dimethylamino)methyl)ethyl ester

There total 3 articles about Methacrylic acid, 2-(dimethylamino)-1-((dimethylamino)methyl)ethyl ester which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

1,3-bis-(dimethylamino)propan-2-ol (5966-51-8) → 1,3-bis(dimethylamino)isopropyl methacrylate (21476-57-3)

Guidance literature:

methacrylic acid methyl ester; With 10H-phenothiazine; tris(nonylphenyl)phosphite; 1,4-dimethoxybezene; at 96 ℃; under 760.051 Torr; Heating / reflux;

With oxygen; lithium oxide; at 121 ℃; for 1.66667h;

1,3-bis-(dimethylamino)propan-2-ol; at 107 - 112 ℃; for 5 - 6h; Product distribution / selectivity;

Reference yield:

1,3-bis-(dimethylamino)propan-2-ol (5966-51-8) + methacrylic acid methyl ester (80-62-6,114512-63-9,143476-91-9,25188-98-1,9011-14-7) → 1,3-bis(dimethylamino)isopropyl methacrylate (21476-57-3)

Guidance literature:

With 10H-phenothiazine; sodium methylate; In methanol;

Reference yield:

→ 1,3-bis(dimethylamino)isopropyl methacrylate (21476-57-3)

Guidance literature:

upstream raw materials:

1,3-bis-(dimethylamino)propan-2-ol

methacrylic acid methyl ester

Refernces