4-(2-Pyrrolidinoethyl)piperidine

Base Information

• Chemical Name: 4-(2-Pyrrolidinoethyl)piperidine
• CAS No.: 14759-08-1
• Molecular Formula: C11H22 N2
• Molecular Weight: 182.309
• Hs Code.: 2933990090
• European Community (EC) Number: 604-590-6
• NSC Number: 166304
• DSSTox Substance ID: DTXSID90304569
• Wikidata: Q72505347
• Mol file: 14759-08-1.mol

Synonyms:14759-08-1;4-(2-PYRROLIDINOETHYL)PIPERIDINE;4-(2-(Pyrrolidin-1-yl)ethyl)piperidine;4-[2-(pyrrolidin-1-yl)ethyl]piperidine;4-(2-pyrrolidin-1-ylethyl)piperidine;4-[2-(1-pyrrolidinyl)ethyl]piperidine;4-(2-Pyrrolidin-1-yl-ethyl)-piperidine;Piperidine, 4-[2-(1-pyrrolidinyl)ethyl]-;NSC166304;SCHEMBL640737;C(CN1CCCC1)C2CCNCC2;DTXSID90304569;MFCD03092939;AKOS003594501;NSC 166304;NSC-166304;PS-3204;SB41460;4-(2-pyrrolidine-1-yl-ethyl)-piperidine;CS-0207500;FT-0708586;4-(2-pyrrolidinoethyl)piperidine, AldrichCPR;EN300-1850129

Chemical Property of 4-(2-Pyrrolidinoethyl)piperidine

Chemical Property:

• Vapor Pressure: 0.019mmHg at 25°C
• Boiling Point: 252.8°Cat760mmHg
• PKA: 10.63±0.10(Predicted)
• Flash Point: 90.3°C
• PSA: 15.27000
• Density: 0.93g/cm³
• LogP: 1.73860
• Storage Temp.: 2-8°C
• XLogP3: 1.4
• Hydrogen Bond Donor Count: 1
• Hydrogen Bond Acceptor Count: 2
• Rotatable Bond Count: 3
• Exact Mass: 182.178298710
• Heavy Atom Count: 13
• Complexity: 135

Purity/Quality:

98%min ^*data from raw suppliers

4-[2-(Pyrrolidin-1-yl)ethyl]piperidine ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: C1CCN(C1)CCC2CCNCC2

Technology Process of 4-(2-Pyrrolidinoethyl)piperidine

There total 3 articles about 4-(2-Pyrrolidinoethyl)piperidine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 88.0%

→ 4-(2-(pyrrolidin-1-yl)ethyl)piperidine (14759-08-1)

Guidance literature:

Reference yield:

4-(2-pyrrolidino-ethyl)-pyridine; dihydrochloride (92547-36-9) → 4-(2-(pyrrolidin-1-yl)ethyl)piperidine (14759-08-1)

Guidance literature:

With methanol; platinum; under 2206.5 - 2942.03 Torr; Hydrogenation;

DOI:10.1021/ja01568a046

Reference yield:

4-(2-pyrrolidin-1-yl-ethyl)-pyridine (67580-65-8) → 4-(2-(pyrrolidin-1-yl)ethyl)piperidine (14759-08-1)

Guidance literature:

With acetic acid; platinum; under 2942.03 Torr; Hydrogenation;

upstream raw materials:

4-(2-pyrrolidin-1-yl-ethyl)-pyridine

4-(2-pyrrolidino-ethyl)-pyridine; dihydrochloride

Downstream raw materials:

2-((1-(4-methoxy-2,6-dimethylphenylsulfonyl)piperidin-2-yl)methoxy)-1-(4-(2-(pyrrolidin-1-yl)ethyl)piperidin-1-yl)ethanone

2-((1-(4-methoxy-2,6-dimethylphenylsulfonyl)pyrrolidin-2-yl)methoxy)-1-(4-(2-(pyrrolidin-1-yl)ethyl)piperidin-1-yl)ethanone

4-methoxy-2,6-dimethyl-N-[1-[2-oxo-2-[4-(2-pyrrolidin-1-yl-ethyl)piperidin-1-yl]ethyl]-1H-indol-6-yl]benzenesulfonic acid amide

4-methoxy-N,2,6-trimethyl-N-(2-(4-(4-(2-(pyrrolidin-1-yl)ethyl)piperidin-1-yl)pyrimidin-2-yloxy)ethyl)phenylsulfonamide

Refernces