N-4-chlorobenzylhydroxylamine

Base Information

• Chemical Name: N-4-chlorobenzylhydroxylamine
• CAS No.: 51307-68-7
• Molecular Formula: C₇H₈ClNO
• Molecular Weight: 157.6
• Mol file: 51307-68-7.mol

Synonyms:N-4-chlorobenzylhydroxylamine

Chemical Property of N-4-chlorobenzylhydroxylamine

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of N-4-chlorobenzylhydroxylamine

There total 8 articles about N-4-chlorobenzylhydroxylamine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 97.0%

4-chlorobenzaldoxime (3848-36-0) → N-4-chlorobenzylhydroxylamine (51307-68-7)

Guidance literature:

With hydrogenchloride; sodium cyanoborohydride; In methanol;

DOI:10.1039/b106887n

Reference yield:

→ N-4-chlorobenzylhydroxylamine (51307-68-7) + 4-chlorobenzaldehyde (104-88-1)

Guidance literature:

With hydrogenchloride; Durchleiten von Wasserdampf;

Reference yield:

hydrogenchloride (7647-01-0,15364-23-5) + N-(4-chlorophenyl)methyl-N-(4-chlorophenyl)methyleneamine N-oxide (711014-90-3,154110-60-8) → N-4-chlorobenzylhydroxylamine (51307-68-7) + 4-chlorobenzaldehyde (104-88-1)

Guidance literature:

upstream raw materials:

4-chlorobenzaldoxime

hydrogenchloride

N-(4-chlorophenyl)methyl-N-(4-chlorophenyl)methyleneamine N-oxide

4-chlorobenzaldehyde

Downstream raw materials:

(S)-5-benzyl-2-(4-chlorobenzyl)-3-methyl-1,2,5-oxadiazinan-6-one

(S)-N¹-benzyl-N²-(4-chlorobenzyl)-N²-hydroxypropane-1,2-diamine

benzyl (2-(N-(4-chlorobenzyl)-2,2,2-trifluoroacetamido)cyclopent-2-en-1-yl)carbamate

1-(4-chlorophenyl)-N-cyclopentylidenemethanamine oxide

Refernces

• 1、 Wu, Kaicheng,Chen, Yali,Lin, Yibei,Cao, Weiguo,Zhang, Min,Chen, Jie,Lee, Albert W.M.. "Cycloaddition of nitrones with arynes generated from benzobisoxadisilole or 2,3-naphthoxadisilole". experimental part. p. 578 - 582. Retrieved 2010/09/05.
• 2、 Gopalakrishnan, Mannathusamy,Anandabaskaran, Thirunavukkarasu,Sureshkumar, Purusothaman,Thanusu, Jayaraman,Kumaran, Arumugam K.,Kanagarajan, Vijayakumar. "Phase-transfer catalysis for the synthesis of hydroxylamines from oximes using benzyltriethylammonium borohydride in methanol and under solid-phase conditions". . p. 50 - 51. Retrieved 2007/10/03.