Diethyl acetylenedicarboxylate

Base Information Edit

Chemical Name:Diethyl acetylenedicarboxylate
CAS No.:762-21-0
Molecular Formula:C8H10O4
Molecular Weight:170.165
Hs Code.:29171990
European Community (EC) Number:212-095-8
NSC Number:674446,67975
DSSTox Substance ID:DTXSID20227055
Nikkaji Number:J102.338A
Wikidata:Q72469046
ChEMBL ID:CHEMBL4086918
Mol file:762-21-0.mol

Synonyms:acetylenedicarboxylic acid dimethyl ester;diethyl acetylenedicarboxylate;diethylacetylenedicarboxylate;dimethyl acetylenedicarboxylate

Suppliers and Price of Diethyl acetylenedicarboxylate

Supply Marketing:Edit

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

TRC
Diethyl acetylenedicarboxylate
500mg
$ 45.00

TCI Chemical
Diethyl Acetylenedicarboxylate >96.0%(GC)
250mL
$ 527.00

TCI Chemical
Diethyl Acetylenedicarboxylate >96.0%(GC)
25mL
$ 74.00

SynQuest Laboratories
Diethyl acetylenedicarboxylate
25 g
$ 85.00

SynQuest Laboratories
Diethyl acetylenedicarboxylate
5 g
$ 27.00

Sigma-Aldrich
Diethyl acetylenedicarboxylate 95%
5g
$ 23.30

Sigma-Aldrich
Diethyl acetylenedicarboxylate for synthesis
10 mL
$ 44.58

Sigma-Aldrich
Diethyl acetylenedicarboxylate for synthesis. CAS 762-21-0, molar mass 170.16 g/mol., for synthesis
8415140010
$ 46.60

Sigma-Aldrich
Diethyl acetylenedicarboxylate 95%
25g
$ 74.20

Sigma-Aldrich
Diethyl acetylenedicarboxylate for synthesis. CAS 762-21-0, molar mass 170.16 g/mol., for synthesis
8415140100
$ 268.00

Total 88 raw suppliers

Chemical Property of Diethyl acetylenedicarboxylate Edit

Chemical Property:

Appearance/Colour:clear light yellow liquid
Vapor Pressure:0.0546mmHg at 25°C
Melting Point:1-3 °C
Refractive Index:n20/D 1.443(lit.)
Boiling Point:233.9 °C at 760 mmHg
Flash Point:94.4 °C
PSA：52.60000
Density:1.127 g/cm³
LogP:0.11600
Storage Temp.:0-6°C
Water Solubility.:Soluble in ethanol, ethyl ether, CCl4, Insoluble in water.
XLogP3:1.5
Hydrogen Bond Donor Count:0
Hydrogen Bond Acceptor Count:4
Rotatable Bond Count:4
Exact Mass:170.05790880
Heavy Atom Count:12
Complexity:208

Purity/Quality:

99% ^*data from raw suppliers

Diethyl acetylenedicarboxylate ^*data from reagent suppliers

Safty Information:

Pictogram(s): C
Hazard Codes:C
Statements: 34
Safety Statements: 26-36/37/39-45-25

MSDS Files:

SDS file from LookChem

Total 1 MSDS from other Authors

Useful:

Chemical Classes:Other Classes -> Esters, Other
Canonical SMILES:CCOC(=O)C#CC(=O)OCC
Uses Diethyl acetylenedicarboxylate is used as a protein cross-linker. It is also used in the synthesis of 3,4,5-trisubstituted 2(5H)-furanone derivatives, highly functionalized thiazolidinone derivatives, novel cyclic peroxide glucosides and 4,11-dimesitylbisanthene, soluble bisanthene derivative, via Diels-Alder reaction. Diethyl acetylenedicarboxylate was used in the synthesis of:3,4,5-trisubstituted 2(5H)-furanone derivativeshighly functionalized thiazolidinone derivativesnovel cyclic peroxide glucosides4,11-dimesitylbisanthene, soluble bisanthene derivative, via Diels-Alder reaction

Technology Process of Diethyl acetylenedicarboxylate

There total 20 articles about Diethyl acetylenedicarboxylate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 99.0%

: 13677-32-2,608-83-3
diethyl 2,3-dibromomaleate

: 762-21-0
acetylenedicarboxylic acid diethyl ester

Guidance literature:: With 1,2-dimethyl-1H-indazol-2-ium-3-carboxylate; In acetonitrile; for 0.75h; Reflux; Inert atmosphere;
DOI:10.1055/s-2008-1067215