2-(tert-butyl)-1-nitroethene

Base Information

• Chemical Name: 2-(tert-butyl)-1-nitroethene
• CAS No.: 20429-42-9
• Molecular Formula: C₆H₁₁NO₂
• Molecular Weight: 129.159
• Mol file: 20429-42-9.mol

Synonyms:2-(tert-butyl)-1-nitroethene

Chemical Property of 2-(tert-butyl)-1-nitroethene

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of 2-(tert-butyl)-1-nitroethene

There total 11 articles about 2-(tert-butyl)-1-nitroethene which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 94.0%

3,3-dimethyl-1-nitrobutan-2-ol (58054-88-9) → (E)-3,3-dimethyl-1-nitrobut-1-ene (20429-42-9,165881-29-8)

Guidance literature:

With dicyclohexyl-carbodiimide; copper(l) chloride; In diethyl ether; at 25 ℃; for 17h;

DOI:10.1055/s-1982-30045

Reference yield: 81.8%

nitromethane (75-52-5) + pivalaldehyde (630-19-3) → (E)-3,3-dimethyl-1-nitrobut-1-ene (20429-42-9,165881-29-8)

Guidance literature:

With pyrrolidine anchored in non-ordered mesoporous silica hybrid materials; In toluene; at 150 ℃; for 1h; Sealed tube; Microwave irradiation;

DOI:10.1002/cctc.202101031

Reference yield: 65.0%

C6H12NO3Br → (E)-3,3-dimethyl-1-nitrobut-1-ene (20429-42-9,165881-29-8)

Guidance literature:

With samarium diiodide; In tetrahydrofuran; at 20 ℃; for 2h;

DOI:10.1021/jo0706271

upstream raw materials:

3,3-dimethyl-1-nitrobutan-2-ol

1-cyclohexyl-2-nitroethanol

pivalaldehyde

nitromethane

Downstream raw materials:

biphenyl

(1S,2R,1'R)-(-)-N-<2-(2',2'-dimethyl-1'-nitromethylpropoxy)-1-methyl-2-phenylethyl>formamide

Refernces

• 1、 Llopis, Sebastián,Velty, Alexandra,Díaz, Urbano. "Active Base Hybrid Organosilica Materials based on Pyrrolidine Builder Units for Fine Chemicals Production". . p. 5012 - 5024. Retrieved 2021/10/19.
• 2、 Zhang, Xiaojie,Beaudry, Christopher M.. "Synthesis of Highly Substituted Phenols and Benzenes with Complete Regiochemical Control". supporting information. p. 6086 - 6090. Retrieved 2020/08/12.