Disodium cyclohexoxycarbonylphosphonate

Base Information

• Chemical Name: Disodium cyclohexoxycarbonylphosphonate
• CAS No.: 72305-04-5
• Molecular Formula: C₇H₁₁O₅P*2Na
• Molecular Weight: 252.115
• Mol file: 72305-04-5.mol

Synonyms:Disodium cyclohexoxycarbonylphosphonate

Chemical Property of Disodium cyclohexoxycarbonylphosphonate

Chemical Property:

Purity/Quality:

Safty Information:

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MSDS Files:

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Technology Process of Disodium cyclohexoxycarbonylphosphonate

There total 2 articles about Disodium cyclohexoxycarbonylphosphonate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 87.0%

dimethyl cyclohexoxycarbonylphosphonate (72304-82-6) → Disodium cyclohexoxycarbonylphosphonate (72305-04-5)

Guidance literature:

With trimethylsilyl bromide; Amberlite IRC 50 (Na⁺ form); for 3h; Ambient temperature;

DOI:10.1021/jm00356a028

Reference yield:

cyclohexyl chloroformate (13248-54-9) → Disodium cyclohexoxycarbonylphosphonate (72305-04-5)

Guidance literature:

Multi-step reaction with 2 steps

1: 64 percent

2: 87 percent / 1.) bromotrimethylsilane, 2.) Amberlite IRC 50 (Na⁺ form) / 3 h / Ambient temperature

With trimethylsilyl bromide; Amberlite IRC 50 (Na⁺ form);

DOI:10.1021/jm00356a028

upstream raw materials:

dimethyl cyclohexoxycarbonylphosphonate

cyclohexyl chloroformate

Refernces

• 1、 -. "Phosphonoformic acid esters and pharmaceutical compositions containing same". . . Retrieved 2008/06/13.