3-Bromo-1-benzothiophene

Base Information

• Chemical Name: 3-Bromo-1-benzothiophene
• CAS No.: 7342-82-7
• Molecular Formula: C8H5 Br S
• Molecular Weight: 213.098
• Hs Code.: 2934999090
• Mol file: 7342-82-7.mol

Synonyms:Thianaphthene,3-bromo- (5CI); 3-Bromo-1-benzothiophene; 3-Bromobenzo[b]thiophene;3-Bromobenzothiophene; 3-Bromothianaphthene; 3-Bromothionaphthene

Chemical Property of 3-Bromo-1-benzothiophene

Chemical Property:

• Vapor Pressure: 0.00503mmHg at 25°C
• Melting Point: 146-156 °C
• Refractive Index: n20/D 1.668(lit.)
• Boiling Point: 269 ºC
• Flash Point: >230 °F
• PSA: 28.24000
• Density: 1.629
• LogP: 3.66380
• Storage Temp.: Keep in dark place,Sealed in dry,Room Temperature
• Solubility.: Sparingly Soluble (0.14 g/L) (25°C).

Purity/Quality:

98%,99%, ^*data from raw suppliers

3-Bromo-1-benzothiophene ^*data from reagent suppliers

Safty Information:

• Hazard Codes: Xi
• Statements: 36/37/38
• Safety Statements: 26-37/39

MSDS Files:

SDS file from LookChem

Total 1 MSDS from other Authors

Useful:

• Uses: Antifungal activity of synthetic di (hetero) arylamines based on the benzo [b] thiophene moiety. 3-Bromothianaphthene may be used in the synthesis of (benzo[b]thiophen-3-yl)trimethylstannane.

Technology Process of 3-Bromo-1-benzothiophene

There total 11 articles about 3-Bromo-1-benzothiophene which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 100.0%

Benzo[b]thiophene (95-15-8,11095-43-5) → 3-Bromothianaphthene (7342-82-7)

Guidance literature:

With N-Bromosuccinimide; acetic acid; In chloroform; at 0 - 20 ℃; for 28h;

DOI:10.1016/j.tet.2004.02.011

Reference yield: 96.0%

benzo[b]thiophen-3-yltriethylgermane → 3-Bromothianaphthene (7342-82-7)

Guidance literature:

With N-Bromosuccinimide; In N,N-dimethyl-formamide; at 20 ℃; for 4h;

DOI:10.1002/anie.202008372

Reference yield: 90.0%

benzo[b]thiophene-3-carboxylic acid (5381-25-9) → 3-Bromothianaphthene (7342-82-7)

Guidance literature:

With potassium phosphate; tetrabuthylammonium tribromide; In acetonitrile; at 100 ℃;

DOI:10.1039/c8sc01016a

upstream raw materials:

Benzo[b]thiophene

benzyne

3,4-dibromothiophene

N-Bromosuccinimide

Downstream raw materials:

3-(1-piperidinyl)benzothiophene

2-(piperidin-1-yl)-1-benzothiophene

Benzo[b]thiophene

3-bromobenzothiophene S,S-dioxide

Refernces

• 1、 Yoshida, Kyohei,Kuwahara, Yutaka,Miyamoto, Koji,Nakashima, Seiya,Jintoku, Hirokuni,Takafuji, Makoto,Ihara, Hirotaka. "A room-Temperature phosphorescent polymer film containing a molecular web based on one-dimensional chiral stacking of a simple luminophore". . p. 5044 - 5047. Retrieved 2017.
• 2、 Zhang, Kai,Zhang, Ji,Huang, Lanqi,Zhang, Xiaoqin,Yu, Gui,Wong, Man Shing. "Structure-property relationships of benzo[2,1-b:3,4-b']bis[1]benzothiophenes for organic field effect transistors". . p. 2717 - 2721. Retrieved 2018.
• 3、 -. "Thermally activated delayed fluorescent deep blue light material and preparation method thereof with organic electroluminescent device". Paragraph 0091-0095. . Retrieved 2022/01/08.
• 4、 Christmann, Mathias,He, Guoli,List, Benjamin. "Unified Synthesis of Polycyclic Alkaloids by Complementary Carbonyl Activation**". supporting information. p. 13591 - 13596. Retrieved 2021/05/07.