Propylthiourea

Base Information

• Chemical Name: Propylthiourea
• CAS No.: 927-67-3
• Molecular Formula: C4H10N2S
• Molecular Weight: 118.203
• Hs Code.: 2930909090
• European Community (EC) Number: 213-158-2
• DSSTox Substance ID: DTXSID20239113
• Nikkaji Number: J247.957E
• Mol file: 927-67-3.mol

Synonyms:Propylthiourea;927-67-3;n-propylthiourea;1-Propyl-2-thiourea;1-propylthiourea;Propyl-2-thiourea;Thiourea, propyl-;EINECS 213-158-2;N-(n-Propyl)thiourea;propyl isothiourea;Thiourea,N-propyl-;SCHEMBL145524;SCHEMBL9191057;DTXSID20239113;CHEBI:180509;MFCD00041195;AKOS001064974;NCGC00341605-01;BS-23683;CS-0128708;FT-0682130;EN300-08482;D86341;AB01332717-02;A844334;Propylthiourea, PESTANAL(R), analytical standard;Z56930715;3-(1-Thioureido)propyl, functionalized silica gel, 200-400 mesh, extent of labeling: 1.1 mmol/g loading

Chemical Property of Propylthiourea

Chemical Property:

• Vapor Pressure: 0.825mmHg at 25°C
• Melting Point: 120 °C
• Refractive Index: 1.537
• Boiling Point: 182.1 °C at 760 mmHg
• PKA: 14.83±0.29(Predicted)
• Flash Point: 63.9 °C
• PSA: 70.14000
• Density: 1.054 g/cm³
• LogP: 1.32080
• XLogP3: 0.5
• Hydrogen Bond Donor Count: 2
• Hydrogen Bond Acceptor Count: 1
• Rotatable Bond Count: 2
• Exact Mass: 118.05646950
• Heavy Atom Count: 7
• Complexity: 62.7

Purity/Quality:

99% ^*data from raw suppliers

Propylthiourea ^*data from reagent suppliers

Safty Information:

• Pictogram(s): R20/21/22:Harmful by inhalation, in contact with skin and if swallowed.
• Hazard Codes: Xn
• Statements: 20/21/22-22
• Safety Statements: 22-36/37/39

MSDS Files:

SDS file from LookChem

Total 1 MSDS from other Authors

Useful:

• Canonical SMILES: CCCNC(=S)N
• Uses: Metal Scavenger: Pd, Pt, Rh, Ru, and Hg

Technology Process of Propylthiourea

There total 11 articles about Propylthiourea which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 54.0%

→ propylthiourea (927-67-3)

Guidance literature:

Reference yield: 13.0%

1-Methyl-3-{4-phenyl-5-[(E)-propylimino]-4,5-dihydro-[1,2,4]thiadiazol-3-yl}-thiourea (137526-95-5) → propylthiourea (927-67-3) + 6-Imino-1-phenyl-3-propyl-[1,3,5]triazinane-2,4-dithione

Guidance literature:

With ammonium hydroxide; hydrogen sulfide; Heating;

Reference yield: 12.0%

1-Ethyl-3-{5-[(E)-propylimino]-4-p-tolyl-4,5-dihydro-[1,2,4]thiadiazol-3-yl}-thiourea (137527-00-5) → propylthiourea (927-67-3) + 6-Imino-3-propyl-1-p-tolyl-[1,3,5]triazinane-2,4-dithione

Guidance literature:

With ammonium hydroxide; hydrogen sulfide; Heating;

upstream raw materials:

propylamine

O-ethyl thiocarbamate

n-Propyl isothiocyanate

N-tert-butyl-N'-propyl-thiourea

Downstream raw materials:

6-iodo-3-propyl-2-thioxo-2,3-dihydroquinazolin-4(1H)-one

5-(8-phenyl-[1,2,4]triazolo[4,3-a]pyridin-6-yl)-N-propylthiazol-2-amine

6-phenyl-5-[2''-hydroxynaphthyl-(1'')-methyl]-1-propyl-2-thioxo-2,3-dihydro-1H-pyrimidin-4-one

N-(tert-butoxycarbonyl)-N’-(propyl)thiourea

Refernces

• 1、 Fatimi,Lagorce,Chabernaud,Comby,Buxeraud,Raby. "Synthesis and antithyroid activity of 1,4,5-trialkyl 2-thioimidazole derivatives". . p. 253 - 257. Retrieved 2007/10/02.
• 2、 -. "Acyl amidine and acyl, guanidine substituted biphenyl derivatives". . . Retrieved 2008/06/13.