1-(3'-bromo-3'-deoxyarabinofuranosyl)uracil

Base Information

• Chemical Name: 1-(3'-bromo-3'-deoxyarabinofuranosyl)uracil
• CAS No.: 6206-18-4
• Molecular Formula: C₉H₁₁BrN₂O₅
• Molecular Weight: 307.101
• Mol file: 6206-18-4.mol

Synonyms:Uracil,1-(3-bromo-3-deoxy-b-D-arabinofuranosyl)- (7CI,8CI)

Chemical Property of 1-(3'-bromo-3'-deoxyarabinofuranosyl)uracil

Chemical Property:

• PSA: 96.64000
• Density: 1.882g/cm³
• LogP: 2.35990

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of 1-(3'-bromo-3'-deoxyarabinofuranosyl)uracil

There total 2 articles about 1-(3'-bromo-3'-deoxyarabinofuranosyl)uracil which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 70.0%

1-(3-bromo-3-deoxy-5-O-trityl-β-D-arabinofuranosyl)uracil (96253-17-7) → 1-(3'-Brom-3'-desoxy-β-D-arabinofuranosyl)-uracil (6206-18-4)

Guidance literature:

With water; acetic acid; at 90 ℃; for 0.5h;

DOI:10.1021/jm100165w

Reference yield:

→ 1-(3'-Brom-3'-desoxy-β-D-arabinofuranosyl)-uracil (6206-18-4)

Guidance literature:

2,2'-Anhydro-1-<3'-brom-3'-desoxy-β-D-arabinofuranosyl>-uracil/verd.HCl;

upstream raw materials:

1-(3-bromo-3-deoxy-5-O-trityl-β-D-arabinofuranosyl)uracil

Refernces

• 1、 Hollenberg,Watanabe,Fox. "Nucleosides. 102. Synthesis of some 3' deoxy 3' substituted arabinofuranosylpyrimidine nucleosides". . p. 113 - 116. Retrieved 2007/10/09.