10-Fluorodecanoic acid

Base Information

• Chemical Name: 10-Fluorodecanoic acid
• CAS No.: 334-59-8
• Molecular Formula: C10H19FO2
• Molecular Weight: 190.26
• Hs Code.: 2915900090
• DSSTox Substance ID: DTXSID90187036
• Nikkaji Number: J40.815H
• Wikidata: Q83058560
• Metabolomics Workbench ID: 1733
• Mol file: 334-59-8.mol

Synonyms:10-Fluorodecanoic acid;334-59-8;10-fluoro-capric acid;DECANOIC ACID, 10-FLUORO-;omega-Fluorodecanoic acid;10-fluoro-decanoic acid;Kyselina 10-fluordekanova [Czech];Kyselina 10-fluordekanova;BRN 1765020;10:0(10F);10-Fluorocapric acid;SCHEMBL434540;DTXSID90187036;CHEBI:137794;LMFA01090047;BS-48903;LS-59359;E75273

Chemical Property of 10-Fluorodecanoic acid

Chemical Property:

• Vapor Pressure: 0.000445mmHg at 25°C
• Melting Point: 49°C
• Boiling Point: 292.7°C at 760 mmHg
• PKA: 4.78±0.10(Predicted)
• Flash Point: 130.8°C
• PSA: 37.30000
• Density: 0.982g/cm³
• LogP: 3.16130
• XLogP3: 3.6
• Hydrogen Bond Donor Count: 1
• Hydrogen Bond Acceptor Count: 3
• Rotatable Bond Count: 9
• Exact Mass: 190.13690801
• Heavy Atom Count: 13
• Complexity: 126

Purity/Quality:

98%min ^*data from raw suppliers

10-Fluorodecanoicacid 97% ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: C(CCCCC(=O)O)CCCCF

Technology Process of 10-Fluorodecanoic acid

There total 9 articles about 10-Fluorodecanoic acid which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 82.0%

10-fluorodecanoic acid ethyl ester (353-03-7) → 10-fluorodecanoic acid (334-59-8)

Guidance literature:

With potassium hydroxide; In methanol; water; at 20 ℃; for 1h;

DOI:10.1021/jacs.9b06643

Reference yield:

10-fluoro-decan-1-ol (334-64-5) → 10-fluorodecanoic acid (334-59-8)

Guidance literature:

With chromium(VI) oxide; acetic acid;

DOI:10.1021/ja01591a062

Reference yield:

10-Fluor-decansaeure-methylester (1995-63-7) → 10-fluorodecanoic acid (334-59-8)

Guidance literature:

With sodium hydroxide; In methanol; water; at 40 ℃; for 6h; Inert atmosphere;

DOI:10.1002/anie.201706893

upstream raw materials:

1-chloro-9-fluoro-nonane

10-fluoro-decan-1-ol

11-bromoundecanoic acid

methyl 10-hydroxydecanoate

Downstream raw materials:

methyl 18-fluorostearate

1,18-difluoro-octadecane

12-fluoro-3-oxo-dodecanoic acid ethyl ester

10-fluoro-decanoic acid anilide

Refernces

• 1、 Zhao, Yizhou,Chen, Yifeng,Newhouse, Timothy R.. "Allyl-Palladium-Catalyzed α,β-Dehydrogenation of Carboxylic Acids via Enediolates". . p. 13122 - 13125. Retrieved 2017/09/13.