dl-O-Phosphoserine

Base Information

• Chemical Name: dl-O-Phosphoserine
• CAS No.: 17885-08-4
• Molecular Formula: C3H8 N O6 P
• Molecular Weight: 185.073
• Hs Code.: 2931900090
• European Community (EC) Number: 241-834-7
• NSC Number: 90791
• UNII: 6GV29P6OZA
• DSSTox Substance ID: DTXSID00859358
• Nikkaji Number: J2.923.684D
• Wikipedia: Phosphoserine
• Wikidata: Q104950626
• NCI Thesaurus Code: C118883
• Metabolomics Workbench ID: 37880
• ChEMBL ID: CHEMBL180002
• Mol file: 17885-08-4.mol

Synonyms:Phosphate, Serine;Phosphate, Seryl;Phosphorylserine;Phosphoserine;Serine Phosphate;Seryl Phosphate

Chemical Property of dl-O-Phosphoserine

Chemical Property:

• Vapor Pressure: 9.3E-15mmHg at 25°C
• Melting Point: 190 °C(lit.)
• Boiling Point: 475.4°Cat760mmHg
• Flash Point: 241.3°C
• PSA: 139.89000
• Density: 1.809g/cm³
• LogP: -0.79210
• Storage Temp.: -15°C
• Solubility.: H2O: 50 mg/mL hot, clear, colorless to slightly yellow
• XLogP3: -5.1
• Hydrogen Bond Donor Count: 4
• Hydrogen Bond Acceptor Count: 7
• Rotatable Bond Count: 4
• Exact Mass: 185.00892397
• Heavy Atom Count: 11
• Complexity: 186

Purity/Quality:

98%, ^*data from raw suppliers

O-Phospho-DL-serine ^*data from reagent suppliers

Safty Information:

• Pictogram(s): Xi
• Hazard Codes: Xi
• Statements: 36/37/38
• Safety Statements: 26

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: C(C(C(=O)O)N)OP(=O)(O)O
• Uses: DL-O-Phosphoserine is used in alternative pathways for biosynthesis of cysteine and of selenocysteine.

Technology Process of dl-O-Phosphoserine

There total 9 articles about dl-O-Phosphoserine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

serin (302-84-1,83245-15-2) → O-phospho-DL-serine (17885-08-4,7331-08-0)

Guidance literature:

With phosphoric acid; phosphorus pentoxide; at 20 ℃;

Reference yield:

N-benzyloxycarbonyl-O-diphenoxyphosphoryl-DL-serine benzyl ester (89019-92-1) → O-phospho-DL-serine (17885-08-4,7331-08-0)

Guidance literature:

Hydrogenation;

Reference yield:

O-diphenoxyphosphoryl-DL-serine ethyl ester; hydrobromide → O-phospho-DL-serine (17885-08-4,7331-08-0)

Guidance literature:

With sodium hydroxide;

upstream raw materials:

serin

N-benzyloxycarbonyl-O-diphenoxyphosphoryl-DL-serine benzyl ester

phosphoric acid

Downstream raw materials:

L-phosphoserine

D-Serine

L-serin

O-phospho-D-serine

Refernces