3-Methyl-6-methylaminouracil

Base Information

• Chemical Name: 3-Methyl-6-methylaminouracil
• CAS No.: 5759-63-7
• Molecular Formula: C6H9N3O2
• Molecular Weight: 155.156
• Hs Code.: 2933599090
• Mol file: 5759-63-7.mol

Synonyms:3-methyl-6-(methylamino)pyrimidine-2,4(1H,3H)-dione;2,4(1H,3H)-pyrimidinedione, 3-methyl-6-(methylamino)-;3-Methyl-6-(methylamino)uracil;3-Methyl-6-(methylamino)pyrimidine-2,4(1H,3H)-dione;

Chemical Property of 3-Methyl-6-methylaminouracil

Chemical Property:

• Refractive Index: 1.566
• PSA: 66.89000
• Density: 1.3 g/cm³
• LogP: -0.81170

Purity/Quality:

98% or more ^*data from raw suppliers

3-METHYL-6-METHYLAMINOURACIL 95.00% ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of 3-Methyl-6-methylaminouracil

There total 2 articles about 3-Methyl-6-methylaminouracil which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 76.0%

3-methyl-6-chlorouracil (4318-56-3) + methylamine (74-89-5) → 6-methylamino-3-methyluracil (5759-63-7)

Guidance literature:

In water; at 120 - 130 ℃; for 2h;

DOI:10.1135/cccc19921314

Reference yield:

→ 6-methylamino-3-methyluracil (5759-63-7)

Guidance literature:

6(α-Methylhydrazino)-3-methyluracil (4), H2, Raney-Ni;

Reference yield: 94.0%

(Z)-β-chloro-α-(ethoxycarbonyl)cinnamaldehyde (31357-80-9) + 6-methylamino-3-methyluracil (5759-63-7) → ethyl 2,3,4,8-tetrahydro-3-methyl-2,4-dioxopyrido-7-phenyl-8-methyl<2,3-d>pirimidine-6-carboxylate (85103-14-6)

Guidance literature:

In N,N-dimethyl-formamide; at 90 ℃; for 3h;

DOI:10.3987/com-04-10063

upstream raw materials:

3-methyl-6-chlorouracil

methylamine

Downstream raw materials:

C₂₀H₂₄N₆O₄

5,5'-p-chlorophenylmethylenebis(6-methylamino-3-methyluracil)

C₁₉H₂₂N₆O₄

C₁₉H₂₂N₆O₅

Refernces

• 1、 Bozoova, Alena,Rybar, Alfonz,Alfoeldi, Juraj,Basnakova, Gabriela. "3-ALKYL-6-METHYL-5,7-DIOXO-4,5,6,7-TETRAHYDRO-1,2,3-TRIAZOLOPYRIMIDINES AND THEIR ALKYLATIONS". . p. 1314 - 1325. Retrieved 2007/10/02.