sodium salt of p-toluoylacetaldehyde

Base Information

• Chemical Name: sodium salt of p-toluoylacetaldehyde
• CAS No.: 53073-02-2
• Molecular Formula: C₁₀H₉O₂*Na
• Molecular Weight: 184.17
• Mol file: 53073-02-2.mol

Synonyms:sodium salt of p-toluoylacetaldehyde

Chemical Property of sodium salt of p-toluoylacetaldehyde

Chemical Property:

Purity/Quality:

Safty Information:

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MSDS Files:

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Technology Process of sodium salt of p-toluoylacetaldehyde

There total 1 articles about sodium salt of p-toluoylacetaldehyde which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

para-methylacetophenone (122-00-9) + formic acid ethyl ester (109-94-4) → sodium salt of p-toluoylacetaldehyde (53073-02-2)

Guidance literature:

para-methylacetophenone; With sodium; In toluene; for 0.5h; Cooling with ice;

formic acid ethyl ester; In toluene; at 20 ℃; for 17h; Cooling with ice;

DOI:10.1016/j.ejmech.2008.03.010

Reference yield: 69.0%

sodium salt of p-toluoylacetaldehyde (53073-02-2) → para-methylacetophenone (122-00-9)

Guidance literature:

In water; at 150 ℃; for 2h; High pressure; Sealed tube;

DOI:10.1021/jo301979p

Reference yield: 68.0%

N-methoxylamine hydrochloride (593-56-6) + sodium salt of p-toluoylacetaldehyde (53073-02-2) → 3-oxo-3-p-tolylpropanal oxime methyl ether (477851-40-4)

Guidance literature:

In ethanol; at 20 ℃;

DOI:10.1016/j.ejmech.2008.03.010

upstream raw materials:

para-methylacetophenone

formic acid ethyl ester

Downstream raw materials:

3-dimethylamino-1-(4-methyl-phenyl)-2-propen-1-one

2-diazo-1-(4-methylphenyl)ethanone

Bis<2-(p-toluoyl)vinyl>-aether

5-p-Tolyl-4,5-dihydro-isoxazol-5-ol

Refernces

• 1、 Liu, Jinbing,Cao, Rihui,Wu, Qifeng,Ma, Chunming,Wang, Zihou,Peng, Wenlie,Song, Huacan. "Synthesis and antibacterial evaluation of novel 4-alkyl substituted phenyl β-aldehyde ketone derivatives". experimental part. p. 1737 - 1744. Retrieved 2009/05/30.