2-(Diethylamino)ethyl acrylate

Base Information

• Chemical Name: 2-(Diethylamino)ethyl acrylate
• CAS No.: 2426-54-2
• Deprecated CAS: 496937-74-7
• Molecular Formula: C9H17 N O2
• Molecular Weight: 171.239
• Hs Code.: 2922199090
• European Community (EC) Number: 219-378-5
• NSC Number: 3118
• UN Number: 1993
• UNII: J4T0T1RP9Z
• DSSTox Substance ID: DTXSID4051900
• Nikkaji Number: J33.795A
• Wikidata: Q27281204
• Mol file: 2426-54-2.mol

Synonyms:2-(DIETHYLAMINO)ETHYL ACRYLATE;2426-54-2;Diethylaminoethyl acrylate;2-(Diethylamino)-ethyl acrylate;N,N-Diethylaminoethyl acrylate;Ageflex FA-2;2-(diethylamino)ethyl prop-2-enoate;Acrylic acid, 2-(diethylamino)ethyl ester;NSC 3118;2-Propenoic acid, 2-(diethylamino)ethyl ester;HSDB 5460;EINECS 219-378-5;UNII-J4T0T1RP9Z;BRN 1099061;J4T0T1RP9Z;2-Diethylaminoethylester kyseliny akrylove;Acrylic acid, N,N-diethylaminoethyl ester;N.N-Diethylamino ethylacrylate;AI3-03840;DTXSID4051900;2-Diethylaminoethylester kyseliny akrylove [Czech];NSC-3118;.beta.-(Diethylamino)ethyl acrylate;(Diethylamino)ethyl acrylate;SCHEMBL14924;2-(diethylamino)ethylacrylate;2-(Diethlamino) ethyl acrylate;DTXCID9030462;WLN: 2N2&2OV1U1;N,N-(Diethylamino)ethyl acrylate;NSC3118;Tox21_303835;MFCD00042882;2-(N',N'-diethylamino)ethylacrylate;2-(Diethylamino)ethyl acrylate, 95%;AKOS015903281;N-(acryloyloxyethyl)-N,N-diethyl amine;Acrylic acid,N-(diethylamino)ethyl ester;NCGC00357108-01;AS-81259;CAS-2426-54-2;Acrylic acid, N,N-(diethylamino)ethyl ester;D5927;FT-0634265;2-(DIETHYLAMINO)ETHYL ACRYLATE [HSDB];J-015423;Q27281204;2-Propenoic acid, 2-methyl- 2-(diethylamino)ethyl ester;2-(Diethylamino)ethyl acrylate, 95%, contains 25 ppm monomethyl ether hydroquinone as inhibitor

Chemical Property of 2-(Diethylamino)ethyl acrylate

Chemical Property:

• Vapor Pressure: 0.77 psi ( 20 °C)
• Melting Point: -60°C
• Refractive Index: n20/D 1.443(lit.)
• Boiling Point: 199 ºC
• PKA: 9.20±0.25(Predicted)
• Flash Point: 165 ºF
• PSA: 29.54000
• Density: 0.922
• LogP: 1.05740
• XLogP3: 1.2
• Hydrogen Bond Donor Count: 0
• Hydrogen Bond Acceptor Count: 3
• Rotatable Bond Count: 7
• Exact Mass: 171.125928785
• Heavy Atom Count: 12
• Complexity: 142

Purity/Quality:

98%,99%, ^*data from raw suppliers

2-(Diethylamino)ethyl acrylate 95%, contains 25 ppm monomethyl ether hydroquinone as inhibitor ^*data from reagent suppliers

Safty Information:

• Hazard Codes: T
• Statements: 22-24-34-43
• Safety Statements: 26-36/37/39-45

MSDS Files:

SDS file from LookChem

Useful:

• Chemical Classes: Plastics & Rubber -> (Meth)acrylates
• Canonical SMILES: CCN(CC)CCOC(=O)C=C

Technology Process of 2-(Diethylamino)ethyl acrylate

There total 6 articles about 2-(Diethylamino)ethyl acrylate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 93.0%

2-(diethylamino)ethyl 3-(dimethylamino)propionate (100536-62-7) → 2-diethylaminoethyl acrylate (2426-54-2)

Guidance literature:

With 2-chloro-4,6-dimethoxy-1 ,3,5-triazine; triethylamine; In dichloromethane; at 20 ℃; for 0.25h;

DOI:10.1016/j.tetlet.2013.01.092

Reference yield: 57.0%

acryloyl chloride (814-68-6,25189-84-8) + 2-(Diethylamino)ethanol (100-37-8) → 2-diethylaminoethyl acrylate (2426-54-2)

Guidance literature:

In acetonitrile; at 0 - 20 ℃; for 17h; Inert atmosphere;

DOI:10.1002/cplu.201700194

Reference yield:

acrylic acid methyl ester (292638-85-8,9003-21-8,96-33-3) + 2-(Diethylamino)ethanol (100-37-8) → 2-diethylaminoethyl acrylate (2426-54-2)

Guidance literature:

With N-Phenyl-2-naphthylamine; aluminum isopropoxide;

DOI:10.1021/ja01177a064

upstream raw materials:

acrylic acid methyl ester

2-(Diethylamino)ethanol

acryloyl chloride

2-chloropropionyl chloride

Downstream raw materials:

3-triethylammonio-propionic acid-(2-triethylammonio-ethyl ester); dibromide

Refernces

• 1、 Yamada, Kohei,Masaki, Kazumasa,Hagimoto, Yuri,Kamiya, Seina,Kunishima, Munetaka. "A new method using 2-chloro-4,6-dimethoxy-1,3,5-triazine for facile elimination of dimethylamino group in Eschenmoser's methylenation for synthesis of α,β-unsaturated esters". supporting information. p. 1758 - 1760. Retrieved 2013/03/29.