Hydrobenzoin

Base Information

• Chemical Name: Hydrobenzoin
• CAS No.: 492-70-6
• Molecular Formula: C14H14O2
• Molecular Weight: 214.264
• Hs Code.: 2906299090
• European Community (EC) Number: 207-758-3
• NSC Number: 133570,14970,10752
• DSSTox Substance ID: DTXSID90870557
• Nikkaji Number: J9.385H
• Wikidata: Q27121684
• ChEMBL ID: CHEMBL365982
• Mol file: 492-70-6.mol

Synonyms:hydrobenzoin

Chemical Property of Hydrobenzoin

Chemical Property:

• Vapor Pressure: 3.18E-06mmHg at 25°C
• Melting Point: 139°C
• Boiling Point: 373°C at 760 mmHg
• PKA: 13.38±0.20(Predicted)
• Flash Point: 179.8°C
• PSA: 40.46000
• Density: 1.193g/cm³
• LogP: 2.45360
• Storage Temp.: Store below +30°C.
• Solubility.: 2.5g/l slightly soluble
• XLogP3: 1.6
• Hydrogen Bond Donor Count: 2
• Hydrogen Bond Acceptor Count: 2
• Rotatable Bond Count: 3
• Exact Mass: 214.099379685
• Heavy Atom Count: 16
• Complexity: 171

Purity/Quality:

98%,99%, ^*data from raw suppliers

Hydrobenzoin ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Chemical Classes: Other Classes -> Other Aromatic Compounds
• Canonical SMILES: C1=CC=C(C=C1)C(C(C2=CC=CC=C2)O)O

Technology Process of Hydrobenzoin

There total 305 articles about Hydrobenzoin which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 95.0%

benzaldehyde (100-52-7) → 1,2-diphenyl-1,2-ethanediol (492-70-6,655-48-1,2325-10-2,38270-73-4,52340-78-0,579-43-1) + benzyl alcohol (100-51-6,185532-71-2)

Guidance literature:

With sodium hydroxide; aluminium; In methanol; water; for 0.0833333h; microwave irradiation;

Reference yield: 89.0%

cis-stilben (645-49-8) → 1,2-diphenyl-1,2-ethanediol (492-70-6,655-48-1,2325-10-2,38270-73-4,52340-78-0,579-43-1) + benzaldehyde (100-52-7)

Guidance literature:

With air; hydroquinone 1,4-phthalazinediyl diether; K2; In water; tert-butyl alcohol; at 50 ℃; for 24h; under 15001.2 Torr; pH=10.4;

DOI:10.1016/S0022-328X(00)00856-1

Reference yield: 83.0%

benzyl alcohol (100-51-6,185532-71-2) → 1,2-diphenyl-1,2-ethanediol (492-70-6,655-48-1,2325-10-2,38270-73-4,52340-78-0,579-43-1) + benzaldehyde (100-52-7)

Guidance literature:

With cadmium(II) sulphide; In acetonitrile; at 20 ℃; for 24h; under 37.5038 Torr; Inert atmosphere; Irradiation;

DOI:10.1039/c2ob07053g

upstream raw materials:

peracetic acid

cis-stilben

(E)-1,2-diphenyl-ethene

2-amino-1,2-diphenylethanol

Downstream raw materials:

4,4'-dinitrobenzil

4,5-diphenyl-[1,3]-dioxolan-2-one

(4S,5R)-2,2-dimethyl-4,5-diphenyl-1,3-dioxolane

phenyl benzyl ketone

Refernces

• 1、 Fujita, Shu,Yamaguchi, Sho,Yamasaki, Jun,Nakajima, Kiyotaka,Yamazoe, Seiji,Mizugaki, Tomoo,Mitsudome, Takato. "Ni2P Nanoalloy as an Air-Stable and Versatile Hydrogenation Catalyst in Water: P-Alloying Strategy for Designing Smart Catalysts". supporting information. p. 4439 - 4446. Retrieved 2021/02/09.
• 2、 Jo, Junhyuk,Kim, Seonyul,Choi, Jun-Ho,Chung, Won-Jin. "A convenient pinacol coupling of diaryl ketones with B2pin2viapyridine catalysis". supporting information. p. 1360 - 1363. Retrieved 2021/02/22.