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Triazolam

Base Information Edit
  • Chemical Name:Triazolam
  • CAS No.:28911-01-5
  • Molecular Formula:C17H12 Cl2 N4
  • Molecular Weight:343.215
  • Hs Code.:2933910000
  • European Community (EC) Number:249-307-3
  • UNII:1HM943223R
  • DSSTox Substance ID:DTXSID6046763
  • Nikkaji Number:J9.291F
  • Wikipedia:Triazolam
  • Wikidata:Q412143
  • NCI Thesaurus Code:C29520
  • RXCUI:10767
  • Pharos Ligand ID:LLG5LABAKL51
  • Metabolomics Workbench ID:43169
  • ChEMBL ID:CHEMBL646
  • Mol file:28911-01-5.mol
Triazolam

Synonyms:Apo Triazo;Apo-Triazo;Gen Triazolam;Gen-Triazolam;Halcion;Triazolam;Trilam;U 33,030;U-33,030;U33,030

 This product is a nationally controlled contraband, and the Lookchem platform doesn't provide relevant sales information.

Chemical Property of Triazolam Edit
Chemical Property:
  • Appearance/Colour:white crystalline powder 
  • Vapor Pressure:1.51E-11mmHg at 25°C 
  • Melting Point:209-212°C 
  • Refractive Index:1.72 
  • Boiling Point:535.6 °C at 760 mmHg 
  • PKA:pKa 1.52(H2O) (Uncertain);6.5(H2O) (Uncertain) 
  • Flash Point:277.7 °C 
  • PSA:43.07000 
  • Density:1.46 g/cm3 
  • LogP:3.66910 
  • Storage Temp.:2-8°C 
  • Water Solubility.:30mg/L(ambient temperature) 
  • XLogP3:2.4
  • Hydrogen Bond Donor Count:0
  • Hydrogen Bond Acceptor Count:3
  • Rotatable Bond Count:1
  • Exact Mass:342.0439018
  • Heavy Atom Count:23
  • Complexity:472
Purity/Quality:
Safty Information:
  • Pictogram(s): ToxicTFlammable
  • Hazard Codes:F,T 
  • Statements: 11-23/24/25-36/38-39/23/24/25 
  • Safety Statements: 22-24/25-26-36-45-36/37-16-7 
MSDS Files:

SDS file from LookChem

Useful:
  • Drug Classes:Sedatives and Hypnotics
  • Canonical SMILES:CC1=NN=C2N1C3=C(C=C(C=C3)Cl)C(=NC2)C4=CC=CC=C4Cl
  • Recent ClinicalTrials:Measurement of the Hippocampal Theta Rhythm From the Outer Ear Canal
  • Recent NIPH Clinical Trials:Study of the effect of modification of slow wave sleep by hypnotics on glucose tolerance in healthy male volunteers
  • Uses Triazolam
  • Therapeutic Function Hypnotic
Technology Process of Triazolam

There total 12 articles about Triazolam which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:
Guidance literature:
With hydrazine hydrate; In ethanol; 1) room temp. 2.5 h; 2) 63 deg C, 3 h.;
DOI:10.1002/jhet.5570170331
Guidance literature:
With toluene-4-sulfonic acid; In N,N-dimethyl-formamide; at 120 ℃; for 1h;
DOI:10.3390/11080583
Guidance literature:
toluene-4-sulfonic acid; In toluene; at 90 - 110 ℃; for 10 - 12h;
Refernces Edit