8-Hydroxyquinolin-1-ium-5-sulfonate

Base Information

• Chemical Name: 8-Hydroxyquinolin-1-ium-5-sulfonate
• CAS No.: 84-88-8
• Molecular Formula: C9H7NO4S
• Molecular Weight: 225.225
• Hs Code.: 29334990
• Mol file: 84-88-8.mol

Synonyms:8-hydroxyquinolin-1-ium-5-sulfonate

Chemical Property of 8-Hydroxyquinolin-1-ium-5-sulfonate

Chemical Property:

• Appearance/Colour: yellow to green crystalline
• Melting Point: 311-313 °C
• Refractive Index: 1.711
• Boiling Point: 432oC
• PKA: pK1:4.092(＋1);pK2:8.776(0) (25°C)
• PSA: 95.87000
• Density: 1.632 g/cm³
• LogP: 2.26790
• Storage Temp.: Inert atmosphere,Room Temperature
• XLogP3: 0.7
• Hydrogen Bond Donor Count: 2
• Hydrogen Bond Acceptor Count: 4
• Rotatable Bond Count: 0
• Exact Mass: 225.00957888
• Heavy Atom Count: 15
• Complexity: 310

Purity/Quality:

99% ^*data from raw suppliers

8-Hydroxy-5-quinolinesulfonicacid ^*data from reagent suppliers

Safty Information:

• Pictogram(s): Xn,Xi
• Hazard Codes: Xn,Xi
• Statements: 22-36-36/37/38
• Safety Statements: 26-36

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: C1=CC2=C(C=CC(=C2[NH+]=C1)O)S(=O)(=O)[O-]

Technology Process of 8-Hydroxyquinolin-1-ium-5-sulfonate

There total 19 articles about 8-Hydroxyquinolin-1-ium-5-sulfonate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 100.0%

8-quinolinol (148-24-3,24804-14-6) → 8-quinolinol-5-sulfonic acid (84-88-8)

Guidance literature:

With oleum; at 20 ℃;

DOI:10.1021/ic300697w DOI:10.1021/ic300697w

Reference yield: 39.0%

2-aminophenol-4-sulfonic acid (98-37-3) + acrolein (107-02-8,25068-14-8) → 8-quinolinol-5-sulfonic acid (84-88-8)

Guidance literature:

With hydrogenchloride; In water; at 100 ℃; for 1h; Inert atmosphere;

DOI:10.1021/jm301544x

Reference yield:

5,12-naphthacenequinone (1090-13-7) → 8-quinolinol-5-sulfonic acid (84-88-8) + benzoic acid (65-85-0,8013-63-6) + naphthalene-2-carboxylate (93-09-4)

Guidance literature:

at 310 ℃;

upstream raw materials:

8-quinolinol

8-chloro-quinoline-5-sulfonic acid

1,2-di[(Ξ)-phthalidyliden]-ethane

sodium methylate

Downstream raw materials:

quinoline-2,8-diol

Pyridine-2,3-dicarboxylic acid

8-aminoquinoline-5-sulphonic acid

8-hydroxy-7-iodo-quinoline-5-sulfonic acid

Refernces

• 1、 Jianbo, He,Tingting, Zhou,Yongjing, Cao,Yuanyuan, Zhang,Weiqing, Yang,Menglin, Ma. "Study on Relationship Between Fluorescence Properties and Structure of Substituted 8-Hydroxyquinoline Zinc Complexes". . p. 1121 - 1126. Retrieved 2018/08/17.
• 2、 Comby, Steve,Tuck, Sarah A.,Truman, Laura K.,Kotova, Oxana,Gunnlaugsson, Thorfinnur. "New trick for an old ligand! The sensing of Zn(II) using a lanthanide based ternary Yb(III)-cyclen-8-hydroxyquinoline system as a dual emissive probe for displacement assay". . p. 10158 - 10168. Retrieved 2013/01/15.