HOMATROPINE METHYL BROMIDE

Base Information

• Chemical Name: HOMATROPINE METHYL BROMIDE
• CAS No.: 80-49-9
• Molecular Formula: C17H24NO3.Br
• Molecular Weight: 370.286
• Hs Code.: 29399990
• European Community (EC) Number: 201-284-0
• Wikipedia: Homatropine_methylbromide
• Wikidata: Q2605497
• NCI Thesaurus Code: C61784
• RXCUI: 27085
• Metabolomics Workbench ID: 145460
• Mol file: 80-49-9.mol

Synonyms:1aH,5aH-Tropanium, 3a-hydroxy-8-methyl-, bromide, mandelate (8CI);8-Methylhomatropinium bromide(6CI,7CI);Camatropine;Helbatropin;Homatrocel;Homatropil;Homolone;Mesopin;Methatropine;Methylhomatropinehydrobromide;NSC 34399;Novatrine;Novatropine;Sethyl;

Chemical Property of HOMATROPINE METHYL BROMIDE

Chemical Property:

• Vapor Pressure: 3.15E-07mmHg at 25°C
• Melting Point: 192 °C
• Refractive Index: 1.588
• Boiling Point: 403.3oC at 760 mmHg
• Flash Point: 197.7oC
• PSA: 46.53000
• Density: 1.21g/cm3
• LogP: -1.00420
• Storage Temp.: -20°C Freezer
• Solubility.: Freely soluble in water, soluble in ethanol 96 per cent
• Hydrogen Bond Donor Count: 1
• Hydrogen Bond Acceptor Count: 4
• Rotatable Bond Count: 4
• Exact Mass: 369.09396
• Heavy Atom Count: 22
• Complexity: 374

Purity/Quality:

99.9% ^*data from raw suppliers

Homatropine methylbromide ^*data from reagent suppliers

Safty Information:

• Statements: 20/21/22
• Safety Statements: 22-26-36

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: C[N+]1(C2CCC1CC(C2)OC(=O)C(C3=CC=CC=C3)O)C.[Br-]
• Uses: Homatropine methylbromide or Methylhomatropine bromide is a quaternary ammonium salt of methylhomatropine. Methylhomatropine is a peripherally acting anticholinergic medication that inhibits muscarinic acetylcholine receptors and thus the parasympathetic nervous system. Methylhomatropine does not cross the blood–brain barrier. Methylhomatropine is used, in addition to papaverine, as component of mild drugs that help "flush" the bile.
• Clinical Use: Homatropine methylbromide is transported poorly acrossthe blood-brain barrier because of its quaternary ammoniumgroup and, therefore, has far fewer stimulant properties thanatropine. It does have all the characteristic peripheralparasympathetic depressant properties of atropine and isused to reduce oversecretion and to relieve GI spasms.