Methyl propyl ether

Base Information

• Chemical Name: Methyl propyl ether
• CAS No.: 557-17-5
• Molecular Formula: C4H10 O
• Molecular Weight: 74.1228
• European Community (EC) Number: 209-158-7
• UN Number: 2612
• UNII: 37D15RN2Z8
• DSSTox Substance ID: DTXSID0074558
• Nikkaji Number: J6.480G
• Wikipedia: Methoxypropane
• Wikidata: Q420967
• Mol file: 557-17-5.mol

Synonyms:1-Methoxypropane;METHYL PROPYL ETHER;557-17-5;Metopryl;Neothyl;Propane, 1-methoxy-;Methyl n-propyl ether;propyl methyl ether;alpha-Methoxy propane;Ether, methyl propyl;EINECS 209-158-7;UNII-37D15RN2Z8;37D15RN2Z8;UN2612;PROPOXY METHYL ETHER;MeOPr;.alpha.-Methoxy propane;1-Methoxypropane, 97%;ALPHA-METHOXYPROPANE;n-C3H7OCH3;Propano, 1-metoxi-(9CI);DTXSID0074558;METHYL PROPYL ETHER [MI];GEO-01712;MFCD00059399;NA2612;UN 2612;LS-67868;M0510;D91344;Methyl propyl ether [UN2612] [Flammable liquid];Q420967;Methyl propyl ether [UN2612] [Flammable liquid]

Chemical Property of Methyl propyl ether

Chemical Property:

• Vapor Pressure: 16.2mmHg at 25°C
• Refractive Index: 1.401
• Boiling Point: 40.1 °C at 760 mmHg
• Flash Point: °C
• PSA: 9.23000
• Density: 0.734 g/cm³
• LogP: 1.04280
• XLogP3: 1.2
• Hydrogen Bond Donor Count: 0
• Hydrogen Bond Acceptor Count: 1
• Rotatable Bond Count: 2
• Exact Mass: 74.073164938
• Heavy Atom Count: 5
• Complexity: 13.1
• Transport DOT Label: Flammable Liquid

Purity/Quality:

98% ^*data from raw suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: CCCOC

Technology Process of Methyl propyl ether

There total 39 articles about Methyl propyl ether which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 68.4%

propargyl alcohol methyl ether (627-41-8) → methyl propyl ether (557-17-5) + methylallylether (627-40-7)

Guidance literature:

With hydrogen; palladium dichloride; In N,N-dimethyl-formamide; for 0.666667h; under 18751.5 Torr; Product distribution; Ambient temperature; various time;

Reference yield:

trimethyl (3-methoxypropyl)tin (80426-24-0) → tetrahydrofuran (109-99-9,24979-97-3,77392-70-2) + methyl propyl ether (557-17-5) + cyclopropyl methyl ether (540-47-6)

Guidance literature:

With benzophenone; In benzene; at 22 ℃; for 72h; Yield given. Yields of byproduct given; Irradiation; further reagents (PhCOMe, (t-BuO)2, FeCl₃);

DOI:10.1021/ja00415a043

Reference yield:

propan-1-ol (71-23-8) + dimethyl sulfate (77-78-1) → methyl propyl ether (557-17-5)

Guidance literature:

With sodium hydroxide; tetra-(n-butyl)ammonium iodide; In chlorobenzene; 1.) ice bath, 1h, 2.) water bath, 2h;

DOI:10.1021/ja00187a017

upstream raw materials:

diazomethane

propan-1-ol

methanol

Dimethyl ether

Downstream raw materials:

1-chloro-4-propoxybutane

butyl methyl ether

2-butyl methyl ether

ethylpropylether

Refernces

• 1、 Ponomarev,Michkov,Dvorko. "Specific features of solvation effects in monomolecular and bimolecular solvolysis". . p. 591 - 598. Retrieved 2001.
• 2、 Fu, Aixiao,Jiang, Shifeng,Liu, Qiang,Liu, Xiaoran,Liu, Xiuyun,Mu, Xindong,Sun, Mengqing,Wang, Xicheng,Xu, Guoqiang,Zhao, Lingling. "Tailoring Interfacial Lewis Acid-Basic Pair on ZnO/4Mg1ZrOx Allows Dehydrogenative α-Methylenation of Alcohols with Methanol to Allylic Alcohols". . . Retrieved 2020/10/07.