Benzenemethanamine, 4-(dimethylamino)-.alpha.-methyl-

Base Information

• Chemical Name: Benzenemethanamine, 4-(dimethylamino)-.alpha.-methyl-
• CAS No.: 91800-15-6
• Molecular Formula: C₁₀H₁₆N₂
• Molecular Weight: 164.25
• Mol file: 91800-15-6.mol

Synonyms:4-(1-aminoethyl)-N,N-dimethylaniline

Chemical Property of Benzenemethanamine, 4-(dimethylamino)-.alpha.-methyl-

Chemical Property:

Purity/Quality:

99% ^*data from raw suppliers

4-(1-Aminoethyl)-n,n-dimethylaniline 95% ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of Benzenemethanamine, 4-(dimethylamino)-.alpha.-methyl-

There total 1 articles about Benzenemethanamine, 4-(dimethylamino)-.alpha.-methyl- which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

p-dimethylaminoacetophenone oxime (6310-87-8) → 4-(1-aminoethyl)-N,N-dimethylaniline (91800-15-6,122779-42-4,942995-65-5)

Guidance literature:

With ammonia; hydrogen; nickel; In methanol; at 75 - 80 ℃; under 73550.8 Torr;

Reference yield:

4-(1-aminoethyl)-N,N-dimethylaniline (91800-15-6,122779-42-4,942995-65-5) + 1-benzyl-5-methyl-1H-1,2,3-triazol-4-carbonyl chloride (664351-09-1) → 1-benzyl-N-{1-[4-(dimethylamino)phenyl]ethyl}-5-methyl-1H-1,2,3-triazole-4-carboxamide

Guidance literature:

With triethylamine; In dichloromethane; at 0 - 20 ℃; for 3h; Schlenk technique; Inert atmosphere;

DOI:10.1021/acs.orglett.7b01672

Reference yield:

4-(1-aminoethyl)-N,N-dimethylaniline (91800-15-6,122779-42-4,942995-65-5) → C10H14Cl2N2

Guidance literature:

With N-chloro-succinimide; at 20 ℃; for 0.166667h; Milling;

DOI:10.1002/ejoc.201700689

upstream raw materials:

p-dimethylaminoacetophenone oxime

Downstream raw materials:

4'-dimethylaminoacetophenone