2-(2-ethylphenyl)-2-propanol

Base Information

• Chemical Name: 2-(2-ethylphenyl)-2-propanol
• CAS No.: 104174-11-0
• Molecular Formula: C₁₁H₁₆O
• Molecular Weight: 164.247
• Mol file: 104174-11-0.mol

Synonyms:2-(2-ethyl-phenyl)-propan-2-ol

Chemical Property of 2-(2-ethylphenyl)-2-propanol

Chemical Property:

Purity/Quality:

99% ^*data from raw suppliers

2-(2-ETHYLPHENYL)-2-PROPANOL ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of 2-(2-ethylphenyl)-2-propanol

There total 5 articles about 2-(2-ethylphenyl)-2-propanol which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

methyl magnesium iodide (917-64-6) + ethyl-benzoic acid methyl ester (50604-01-8) → 2-(2-ethyl-phenyl)-propan-2-ol (104174-11-0)

Guidance literature:

methyl magnesium iodide; ethyl-benzoic acid methyl ester; In diethyl ether; at 0 - 20 ℃; for 3.5h; Inert atmosphere;

With ammonium chloride; In diethyl ether; water; Cooling with ice;

DOI:10.1016/j.tetasy.2011.03.012

Reference yield:

acetone (67-64-1) → 2-(2-ethyl-phenyl)-propan-2-ol (104174-11-0)

Guidance literature:

DOI:10.1021/ja01565a035

Reference yield:

(2-ethylphenyl)magnesium iodide → 2-(2-ethyl-phenyl)-propan-2-ol (104174-11-0)

Guidance literature:

Multi-step reaction with 3 steps

1.1: diethyl ether

2.1: sulfuric acid

3.1: diethyl ether / 3.5 h / 0 - 20 °C / Inert atmosphere

3.2: Cooling with ice

With sulfuric acid; In diethyl ether;

DOI:10.1016/j.tetasy.2011.03.012

upstream raw materials:

methyl magnesium iodide

ethyl ester of ortho-ethylbenzoic acid

acetone

ethyl-benzoic acid methyl ester

Downstream raw materials:

C₁₃H₁₈O₂

C₁₃H₁₈O₂

(S)-2-(2-ethylphenyl)propan-1-ol

(R)-2-(2-ethyl-phenyl)-propanol

Refernces