2-Amino-1-benzylaminobenzimidazole

Base Information

• Chemical Name: 2-Amino-1-benzylaminobenzimidazole
• CAS No.: 124617-77-2
• Molecular Formula: C₁₄H₁₄N₄
• Molecular Weight: 238.292
• Mol file: 124617-77-2.mol

Synonyms:2-Amino-1-benzylaminobenzimidazole

Chemical Property of 2-Amino-1-benzylaminobenzimidazole

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of 2-Amino-1-benzylaminobenzimidazole

There total 3 articles about 2-Amino-1-benzylaminobenzimidazole which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 86.0%

2-Amino-1-benzylideneaminobenzimidazole (122128-68-1) → 2-Amino-1-benzylaminobenzimidazole (124617-77-2)

Guidance literature:

With sodium tetrahydroborate; In methanol; Heating;

DOI:10.1007/BF00479912

Reference yield:

1H-benzimidazol-2-amine (934-32-7) → 2-Amino-1-benzylaminobenzimidazole (124617-77-2)

Guidance literature:

Multi-step reaction with 3 steps

1: 86 percent / hydroxylamine-O-sulfonic acid, KOH / H₂O / 0.5 h / 40 - 45 °C

2: 93 percent / HClO₄ / ethanol / 2 h / Heating

3: 86 percent / NaBH₄ / methanol / Heating

With potassium hydroxide; sodium tetrahydroborate; perchloric acid; hydroxylamine-O-sulfonic acid; In methanol; ethanol; water;

DOI:10.1007/BF00479912

Reference yield:

1,2-diaminobenzimidazole (29540-87-2) → 2-Amino-1-benzylaminobenzimidazole (124617-77-2)

Guidance literature:

Multi-step reaction with 2 steps

1: 93 percent / HClO₄ / ethanol / 2 h / Heating

2: 86 percent / NaBH₄ / methanol / Heating

With sodium tetrahydroborate; perchloric acid; In methanol; ethanol;

DOI:10.1007/BF00479912

upstream raw materials:

2-Amino-1-benzylideneaminobenzimidazole

1H-benzimidazol-2-amine

1,2-diaminobenzimidazole

Downstream raw materials:

2-Benzamido-1-(N-benzylbenzamido)benzimidazole

2-Acetamido-1-(N-benzylacetamido)benzimidazole

Refernces