methyl diphenylsulfonium triflate

Base Information

• Chemical Name: methyl diphenylsulfonium triflate
• CAS No.: 215438-84-9
• Molecular Formula: CF₃O₃S*C₁₄H₁₅S
• Molecular Weight: 364.41
• Mol file: 215438-84-9.mol

Synonyms:methyl diphenylsulfonium triflate

Chemical Property of methyl diphenylsulfonium triflate

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of methyl diphenylsulfonium triflate

There total 4 articles about methyl diphenylsulfonium triflate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 80.0%

trifluorormethanesulfonic acid (1493-13-6) + diphenyl sulfide (139-66-2) + formic acid ethyl ester (109-94-4) → methyl diphenylsulfonium triflate (215438-84-9)

Guidance literature:

at 0 - 20 ℃; for 10h;

DOI:10.1021/jo980473c

Reference yield: 13.0%

trifluorormethanesulfonic acid (1493-13-6) + diphenyl sulfide (139-66-2) + ethyl acetate (141-78-6) → methyl diphenylsulfonium triflate (215438-84-9)

Guidance literature:

at 0 - 20 ℃; for 10h;

DOI:10.1021/jo980473c

Reference yield:

1,1'-sulfinylbisbenzene (945-51-7) → methyl diphenylsulfonium triflate (215438-84-9)

Guidance literature:

Multi-step reaction with 3 steps

1: dichloromethane / 2 h / 0 - 20 °C / Inert atmosphere

2: copper(l) iodide; potassium phosphate; bis(tri-t-butylphosphine)palladium⁽⁰⁾ / N,N-dimethyl-formamide / 15 h / 20 °C / Inert atmosphere; Sealed tube

3: 10 h / 0 - 20 °C / Inert atmosphere

With potassium phosphate; copper(l) iodide; bis(tri-t-butylphosphine)palladium⁽⁰⁾; In dichloromethane; N,N-dimethyl-formamide; 2: |Sonogashira Cross-Coupling;

DOI:10.1021/acs.orglett.7b02764

upstream raw materials:

trifluorormethanesulfonic acid

diphenyl sulfide

ethyl acetate

formic acid ethyl ester

Downstream raw materials:

methyldiphenylsulfonium trifluoromethanesulfonate

4-(phenylethynyl)anisole

1-methoxy-3-(phenylethynyl)benzene

2-phenylethynylanisole

Refernces

• 1、 Wang, Xiao-Yan,Song, Hai-Xia,Wang, Shi-Meng,Yang, Jing,Qin, Hua-Li,Jiang, Xin,Zhang, Cheng-Pan. "Pd-catalyzed Suzuki–Miyaura cross-coupling of [Ph2SR][OTf] with arylboronic acids". . p. 7606 - 7612. Retrieved 2016/11/11.