Virormone

Base Information

• Chemical Name: Virormone
• CAS No.: 58-22-0
• Molecular Formula: C19H28O2
• Molecular Weight: 288.43
• Hs Code.: 29372900
• Mol file: 58-22-0.mol

Synonyms:Agovirin;Eifelfango, Testosteron Propionat;Testosteron propionat Eifelfango;Testosterone Propionate;Virormone

Chemical Property of Virormone

Chemical Property:

• Appearance/Colour: white crystalline odourless solid
• Vapor Pressure: 2.6E-09mmHg at 25°C
• Melting Point: 152-156 °C
• Refractive Index: 1.56
• Boiling Point: 432.9 °C at 760 mmHg
• PKA: 15.06±0.60(Predicted)
• Flash Point: 184.7 °C
• PSA: 37.30000
• Density: 1.12 g/cm³
• LogP: 3.87920
• Storage Temp.: 2-8°C
• Solubility.: 45% (w/v) aq 2-hydroxypropyl-β-cyclodextrin: soluble18.2 mg/ml
• Water Solubility.: 22.79mg/L(20 oC)
• XLogP3: 3.3
• Hydrogen Bond Donor Count: 1
• Hydrogen Bond Acceptor Count: 2
• Rotatable Bond Count: 0
• Exact Mass: 288.208930132
• Heavy Atom Count: 21
• Complexity: 508

Purity/Quality:

99% ^*data from raw suppliers

Testosterone ^*data from reagent suppliers

Safty Information:

• Pictogram(s): T,Xn
• Hazard Codes: T,Xn,F
• Statements: 60-61-11-19-20-40-63-45-36-20/21/22-38
• Safety Statements: 53-45-24/25-36/37-26-16

MSDS Files:

SDS file from LookChem

Total 1 MSDS from other Authors

Useful:

• Canonical SMILES: CC12CCC3C(C1CCC2O)CCC4=CC(=O)CCC34C
• Isomeric SMILES: CC12CCC3C(C1CC[C@@H]2O)CCC4=CC(=O)CCC34C
• Description: Testosterone (Item No.15645) is an analytical reference material categorized as an anabolic androgenic steroid. Testosterone is an endogenous metabolite of androstenedione (Item Nos. ISO60161 | 15874) and estradiol (Item Nos. ISO60155 | 10006315). Anabolic steroids, including testosterone, have been used to enhance physical performance in athletes. Testosterone is regulated as a Schedule III compound in the United States. This product is intended for research and forensic applications. Testosterone (CRM) (Item No. ISO60154) is a certified reference material categorized as an anabolic androgenic steroid. Testosterone is an endogenous metabolite of androstenedione (Item Nos. ISO60161 | 15874) and estradiol (Item Nos. ISO60155 | 10006315). Anabolic steroids, including testosterone, have been used to enhance physical performance in athletes. Testosterone is regulated as a Schedule III compound in the United States. This product is intended for research and forensic applications.
• Uses: Testosterone secreted by the testis is converted to dihydrotestosterone in the target tissues where it appears to mediate many of the biological actions of testosterone. Androgens direct the development of the male phenotype during embryogenesis and at puberty. androgen, antineoplastic Testosterone, Principal hormone of the testes, produced by the interstitial cells. Major circulating androgen; converted by 5α-reductase in androgen-dependent target tissues to 5α-dehydrotestosterone which is required for normal male sexual differentiation. Also converted by aromatization to Estradiol. Testerone is a controlled substance (anabolic steroid). Androgen. Secreted by the testis and is converted to dihydrotestosterone in the target tissue where is appears to mediate many of the biological actions of testosterone. CONTROLLED SUBSTANC

Technology Process of Virormone

There total 224 articles about Virormone which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 100.0%

17β-<(t-butyldimethylsilyl)oxy>androst-4-en-3-one (57711-43-0) → testosterone (58-22-0)

Guidance literature:

With aniline-terephthalaldehyde resin p-toluenesulfonic acid salt; In methanol; at 20 ℃; for 32h;

DOI:10.1016/j.tetlet.2013.09.137

Reference yield: 98.0%

(8R,9S,10R,13S,14S,17S)-10,13-dimethyl-17-((triethylsilyl)oxy)-1,2,6,7,8,9,10,11,12,13,14,15,16,17-tetradecahydro-3H-cyclopenta[a]phenanthren-3-one (61014-73-1) → testosterone (58-22-0)

Guidance literature:

With aniline-terephthalaldehyde resin p-toluenesulfonic acid salt; In methanol; at 20 ℃; for 0.25h;

DOI:10.1016/j.tetlet.2013.09.137

Reference yield: 95.0%

17β-(2'-tetrahydropyranyloxy)androst-4-en-3-one (516-63-2) → testosterone (58-22-0)

Guidance literature:

bis(trimethylsilyl)sulphate; In methanol; 1,2-dichloro-ethane; for 1h; Ambient temperature;

DOI:10.1055/s-1981-29640

upstream raw materials:

pyridine

4β-bromo-17β-hydroxy-5β-androstan-3-one

methanol

3β.17β.3'β.17'β-tetrahydroxy-[3.3']bi[androsten-(4)-yl]

Downstream raw materials:

Testosterone 2-methyl propanoate

3-(3-oxo-4-androsten-17β-oxycarbonyl)propionic acid

3-oxoandrost-4-en-17β-yl butyrate

3-oxo-androst-4-en-17β-yl-methyl formate

Refernces

• 1、 Fujimoto. "-". . p. 1856. Retrieved 1951.
• 2、 Bai, Yin,Zhou, Wen-Di,Mu, Xian-Min,Zhang, Qian,Yu, Chen,Di, Bin,Su, Meng-Xiang. "Covalent Immobilization of Human Placental 17β-Hydroxysteroid Dehydrogenase Type 1 onto Glutaraldehyde Activated Silica Coupled with LC-TOF/MS for Anti-Cancer Drug Screening Applications". . p. 482 - 494. Retrieved 2017.
• 3、 Arnaudi. "". . p. 138. Retrieved 1946.
• 4、 Kim, Mi-Kyeong,Lee, Chi-Ho,Kim, Dae-Duk. "Skin permeation of testosterone and its ester derivatives in rats". . p. 369 - 375. Retrieved 2000.
• 5、 Paz, Gedalia F.,Winter, Jeremy S. D.,Reyes, Francisco I.,Faiman, Charles. "DEVELOPMENTAL PATTERN OF Δ5 3β-HYDROXYSTEROID DEHYDROGENASE ACTIVITY IN ISOLATED RAT LEYDIG CELLS". . p. 661 - 674. Retrieved 1980.
• 6、 Ruzicka,Wettstein,Kaegi. "". . p. 82. Retrieved 1935.
• 7、 Llabrés i Xamena, F. X.,Mautschke, H.-H.. "One-Step Chemo-, Regio- and Stereoselective Reduction of Ketosteroids to Hydroxysteroids over Zr-Containing MOF-808 Metal-Organic Frameworks". . p. 10766 - 10775. Retrieved 2021/06/15.
• 8、 Yildirim, Kudret,Kuru, Ali,Kü?ükba?ol, Eda. "Microbial transformation of androstenedione by Cladosporium sphaerospermum and Ulocladium chartarum". . p. 7 - 14. Retrieved 2019/05/15.