elsholtziaketone

Base Information

• Chemical Name: elsholtziaketone
• CAS No.: 488-05-1
• Molecular Formula: C10H14O2
• Molecular Weight: 166.22
• Mol file: 488-05-1.mol

Synonyms:Isobutyl-3-methyl-2-furyl-keton;elsholtzione;Elsholtziaketon;Elsholtziaketone;2-Isovaleryl-3-methyl-furan;

Chemical Property of elsholtziaketone

Chemical Property:

• Vapor Pressure: 0.0465mmHg at 25°C
• Boiling Point: 236.8°C at 760 mmHg
• Flash Point: 102.8°C
• PSA: 30.21000
• Density: 0.978g/cm³
• LogP: 2.81680

Purity/Quality:

99%, ^*data from raw suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of elsholtziaketone

There total 13 articles about elsholtziaketone which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 90.0%

3-methylfuran-2-carbonyl chloride (22601-06-5) + isobutylmanganese chloride (136208-96-3) → 3-methyl-1-(3-methylfuran-2-yl)butan-1-one (488-05-1)

Guidance literature:

With copper(l) chloride; In tetrahydrofuran; at -10 ℃; for 0.333333h;

DOI:10.1016/S0040-4039(00)79145-3

Reference yield: 81.0%

3-methyl-1-(3-methyl-2-furyl)-1-butanol (82684-26-2,91603-60-0) → 3-methyl-1-(3-methylfuran-2-yl)butan-1-one (488-05-1)

Guidance literature:

With manganese(IV) oxide; In hexane; for 48h; Ambient temperature;

Reference yield: 77.0%

3-methylfuran-2-carbonyl chloride (22601-06-5) + C4H9IMn (90818-29-4) → 3-methyl-1-(3-methylfuran-2-yl)butan-1-one (488-05-1)

Guidance literature:

DOI:10.1016/S0040-4039(00)79145-3

upstream raw materials:

3-methyl-furan-2-carbonitrile

isobutylmagnesium bromide

3-methylfuran-2-carbonyl chloride

C₄H₉IMn

Downstream raw materials:

3-methylbutyric acid

2-furanoic acid

isobutyraldehyde oxime

cis-2-(2-methylpropyl)-4-methyltetrahydropyran

Refernces

• 1、 Cahiez,Chavant,Metais. "A new simple route to furanic ketones; preparation of elsholtzione naginata ketone and perilla ketone". . p. 5245 - 5248. Retrieved 2007/10/02.