Ramoplanin

Base Information

• Chemical Name: Ramoplanin
• CAS No.: 76168-82-6
• Molecular Formula: C106H170ClN21O30
• Molecular Weight: 2254.0597
• Mol file: 76168-82-6.mol

Synonyms:A 16686;A16686A;Antibiotic A 16686;MDL 62198;

Chemical Property of Ramoplanin

Chemical Property:

• Melting Point: 210-230°
• PSA: 852.29000
• LogP: 3.50660
• Storage Temp.: ?20°C
• Solubility.: H2O: soluble10mg/mL

Purity/Quality:

98%min ^*data from raw suppliers

Ramoplanin ^*data from reagent suppliers

Safty Information:

• Pictogram(s): Xi
• Hazard Codes: Xi
• Statements: 41
• Safety Statements: 26-39

MSDS Files:

Useful:

• Description: Ramoplanin (A 16686, A16686A, MDL 62198) is a novel oral nonabsorbable 17-amino-acid cyclic lipoglycodepsipeptide antibiotic from Biosearch Italy. Ramoplanin is an antibiotic complex, first identified in 1984, that was isolated from the fermentation broth of Actinoplanes sp. ATCC 33076. It is a mixture of three closely related compounds, ramoplanin A1–A3, which differ only in the acyl group attached to the Asn-1 N-terminus; ramoplanin A2 is the most abundant.
• Uses: Ramoplanin is a potent cyclic lipoglycodepsipeptide antibiotic that exhibits wide spectrum of antibiotic properties against gram-positive and gram-negative bacteria. Ramoplanin is a complex of three high molecular weight glycolipodepsipeptides, varying in the chain length and shape of the dieneone lipid side-chain. Ramoplanin was isolated in the early 1980s as the major metabolite of a strain of Actinoplanes with antiviral and antibiotic activity against drug resistant Gram positive isolates. Ramoplanin acts by inhibiting cell wall biosynthesis via a different mechanism from the vancomycin-related glycopeptides.