Diethylene glycol diglycidyl ether

Base Information

• Chemical Name: Diethylene glycol diglycidyl ether
• CAS No.: 4206-61-5
• Molecular Formula: C10H18 O5
• Molecular Weight: 218.25
• Hs Code.: 2910900090
• European Community (EC) Number: 224-122-0
• ICSC Number: 0146
• NSC Number: 517936
• UNII: DU5YP0O31R
• DSSTox Substance ID: DTXSID70960086
• Nikkaji Number: J14.464I
• Wikipedia: Diethylene_glycol_diglycidyl_ether
• Wikidata: Q1822640
• Mol file: 4206-61-5.mol

Synonyms:Diethylene glycol diglycidyl ether;4206-61-5;39443-66-8;Diethylene glycol bis-glycidyl ether;Diglycidyl diethyleneglycol ether;EPO-PEG2-EPO;EINECS 224-122-0;UNII-DU5YP0O31R;NSC 517936;BRN 1308085;DU5YP0O31R;Ether, bis(2-(2,3-epoxypropoxy)ethyl);2-[2-[2-(oxiran-2-ylmethoxy)ethoxy]ethoxymethyl]oxirane;Oxirane, 2,2'-(oxybis(2,1-ethanediyloxymethylene))bis-;2-[(2-{2-[(oxiran-2-yl)methoxy]ethoxy}ethoxy)methyl]oxirane;4,7,10-Trioxatridecane, 1,2:12,13-diepoxy-;2,2'-(Oxybis(2,1-ethanediyloxymethylene))bisoxirane;NSC-517936;Oxirane, 2,2'-[oxybis(2,1-ethanediyloxymethylene)]bis-;2,2'-(Oxybis(ethyleneoxymethylene))bisoxirane;Ether, bis[2-(2,3-epoxypropoxy)ethyl];2,2'-[oxybis(ethyleneoxymethylene)]bisoxirane;Ether,3-epoxypropoxy)ethyl];SCHEMBL55331;Diethylenglykol-diglycidylether;C(OCCOCCOCC1CO1)C2CO2;Epoxide-PEG-Epoxide, MW 10K;DTXSID70960086;EPO-PEG-EPO, MW 1,000;EPO-PEG-EPO, MW 2,000;EPO-PEG-EPO, MW 5,000;NSC517936;AKOS030228430;EPO-PEG-EPO, MW 10,000;EPO-PEG-EPO, MW 20,000;BP-25925;BP-25926;BP-25927;BP-25928;BP-25929;LS-67731;FT-0689046;(C3-H5-Cl-O.(C2H4-O)mult-H2-O)x-;4,10-Trioxatridecane, 1,2:12,13-diepoxy-;EN300-255337;Q1822640;Oxirane,2'-[oxybis(2,1-ethanediyloxymethylene)]bis-;2,2'-{Oxybis[(ethane-2,1-diyl)oxymethylene]}bis(oxirane);2-({2-[2-(OXIRAN-2-YLMETHOXY)ETHOXY]ETHOXY}METHYL)OXIRANE

Chemical Property of Diethylene glycol diglycidyl ether

Chemical Property:

• Refractive Index: n20/D 1.467
• Boiling Point: 313°Cat760mmHg
• Flash Point: 127.3°C
• PSA: 52.75000
• Density: 1.165g/cm³
• LogP: -0.16620
• XLogP3: -0.8
• Hydrogen Bond Donor Count: 0
• Hydrogen Bond Acceptor Count: 5
• Rotatable Bond Count: 10
• Exact Mass: 218.11542367
• Heavy Atom Count: 15
• Complexity: 157

Purity/Quality:

DIETHYLENE GLYCOL DIGLYCIDYL ETHER 95.00% ^*data from reagent suppliers

Safty Information:

• Statements: 19

MSDS Files:

Useful:

• Canonical SMILES: C1C(O1)COCCOCCOCC2CO2
• Inhalation Risk: No indication can be given about the rate at which a harmful concentration of this substance in the air is reached on evaporation at 20 °C.
• Effects of Short Term Exposure: The substance is irritating to the eyes, skin and respiratory tract.
• Effects of Long Term Exposure: Repeated or prolonged contact may cause skin sensitization.

Technology Process of Diethylene glycol diglycidyl ether

There total 2 articles about Diethylene glycol diglycidyl ether which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 98.0%

bis(allyloxy)diethylene glycol (57947-82-7,59788-01-1) → diethylene glycol diglycidyl ether (4206-61-5)

Guidance literature:

With 3-chloro-benzenecarboperoxoic acid; In dichloromethane; at 0 - 20 ℃; for 24h; Inert atmosphere;

DOI:10.1055/s-0037-1612249

Reference yield: 68.0%

epichlorohydrin (106-89-8,24969-06-0,13403-37-7) + diethylene glycol (111-46-6) → diethylene glycol diglycidyl ether (4206-61-5)

Guidance literature:

With sodium hydroxide; tetra(n-butyl)ammonium hydrogensulfate; at 40 ℃; for 0.75h;

Reference yield: 73.0%

carbon disulfide (75-15-0,12122-00-8) + diethylene glycol diglycidyl ether (4206-61-5) + phenyl isocyanate (103-71-9) → 5-(9-oxathiolan-2-thione-2,5,8-trioxanonan-5-yl)-3-phenyloxazolidin-2-one

Guidance literature:

diethylene glycol diglycidyl ether; With lithium bromide; In tetrahydrofuran; for 0.5h; Inert atmosphere; Reflux;

phenyl isocyanate; In tetrahydrofuran; Inert atmosphere; Reflux;

carbon disulfide; In tetrahydrofuran; at 20 ℃; for 10h; Inert atmosphere;

DOI:10.1002/jhet.2834

upstream raw materials:

epichlorohydrin

diethylene glycol

bis(allyloxy)diethylene glycol

Downstream raw materials:

1-(2-{2-[2-Hydroxy-3-(4-vinyl-phenoxy)-propoxy]-ethoxy}-ethoxy)-3-(4-vinyl-phenoxy)-propan-2-ol

11-Phenyl-1,4,7-trioxa-11-aza-cyclotetradecane-9,13-diol

Refernces

• 1、 Stefaniak, Monika,Romański, Jaros?aw. "Facile Synthesis of Hydroxy-Substituted Thiacrown Ethers via Nucleophilic Ring Opening of Epoxides". . p. 2214 - 2220. Retrieved 2019/05/10.
• 2、 Stefaniak, Monika,Romański, Jaros?aw. "Application of HPLC for the screening of separation of new macrocyclic systems". . p. 245 - 248. Retrieved 2017/01/22.