4-(Bromomethyl)benzoic acid

Base Information Edit

Chemical Name:4-(Bromomethyl)benzoic acid
CAS No.:6232-88-8
Molecular Formula:C8H7BrO2
Molecular Weight:215.046
Hs Code.:29163900
European Community (EC) Number:228-343-3
NSC Number:56891
DSSTox Substance ID:DTXSID7064154
Nikkaji Number:J208.064H
Wikidata:Q27454562
ChEMBL ID:CHEMBL101846
Mol file:6232-88-8.mol

Synonyms:4-(bromomethyl)benzoic acid

Suppliers and Price of 4-(Bromomethyl)benzoic acid

Supply Marketing:Edit

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

TRC
4-(Bromomethyl)benzoic acid
10g
$ 305.00

TRC
4-(Bromomethyl)benzoic acid
1g
$ 165.00

TCI Chemical
4-(Bromomethyl)benzoic Acid >97.0%(GC)(T)
25g
$ 50.00

TCI Chemical
4-(Bromomethyl)benzoic Acid >97.0%(GC)(T)
5g
$ 18.00

Sigma-Aldrich
4-(Bromomethyl)benzoic acid 97%
50g
$ 311.00

Sigma-Aldrich
Eprosartan Related Compound D United States Pharmacopeia (USP) Reference Standard
15mg
$ 1120.00

Sigma-Aldrich
4-(Bromomethyl)benzoic acid 97%
10g
$ 83.50

Sigma-Aldrich
4-(Bromomethyl)benzoic acid for synthesis. CAS 6232-88-8, chemical formula 4-(BrCH )C H COOH., for synthesis
8219780010
$ 102.00

Sigma-Aldrich
4-(Bromomethyl)benzoic acid 97%
5g
$ 44.00

Oakwood
4-(Bromomethyl)benzoic acid
25g
$ 49.00

Total 122 raw suppliers

Chemical Property of 4-(Bromomethyl)benzoic acid Edit

Chemical Property:

Appearance/Colour:white to beige crystalline powder
Vapor Pressure:7.45E-05mmHg at 25°C
Melting Point:224-229 °C(lit.)
Refractive Index:1.5500 (estimate)
Boiling Point:328.8 °C at 760 mmHg
PKA:4.10±0.10(Predicted)
Flash Point:152.7 °C
PSA：37.30000
Density:1.635 g/cm³
LogP:2.27970
Storage Temp.:Store below +30°C.
Water Solubility.:Soluble in water.
XLogP3:2.4
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:2
Rotatable Bond Count:2
Exact Mass:213.96294
Heavy Atom Count:11
Complexity:139

Purity/Quality:

99% ^*data from raw suppliers

4-(Bromomethyl)benzoic acid ^*data from reagent suppliers

Safty Information:

Pictogram(s): Xi,C
Hazard Codes:Xi,C
Statements: 36/37/38
Safety Statements: 26-36

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:C1=CC(=CC=C1CBr)C(=O)O
Uses 4-(Bromomethyl)benzoic Acid is an intermediate in the synthesis of Eprosartan (E590100), a prototype of the imidazoleacrylic acid angiotensin II receptor antagonists used as an antihypertensive agent. 4-(Bromomethyl)benzoic acid acts as an intermediate in the synthesis of eprosartan, which is used as an antihypertensive agent. Further, it is used in the preparation of 5,10,15,20-tetra(m-hydroxyphenyl)chlorin (temoporfin), which is a second generation photosensitizer. In addition to this, it is used in the preparation of 4-(5-arylidene-2,4-dioxothiazolidin-3-yl) methylbenzoic acids. 4-(Bromomethyl)benzoic acid was used in the chemical modification of 5,10,15,20-tetra(m-hydroxyphenyl)chlorin (temoporfin), second generation photosensitizer. It was also used in the synthesis of 4-(5-arylidene-2,4-dioxothiazolidin-3-yl) methylbenzoic acids.

Technology Process of 4-(Bromomethyl)benzoic acid

There total 24 articles about 4-(Bromomethyl)benzoic acid which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 100.0%